CENPO
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Official Full Name
centromere protein O
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Overview
This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] -
Synonyms
CENPO; centromere protein O; CENP-O; MCM21R; ICEN-36; centromeric protein O; interphase centromere complex protein 36;
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- GST|His
- His
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CENPO-1123H | Recombinant Human CENPO Protein, GST-Tagged | Wheat Germ | GST |
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| Human | CENPO-11101H | Recombinant Human CENPO, GST-tagged | E.coli | GST | 1-300a.a. | |
| Human | CENPO-7578HCL | Recombinant Human CENPO 293 Cell Lysate | HEK293 | N/A |
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| Human | CENPO-3183H | Recombinant Human CENPO Protein, GST/His-tagged | E.coli | GST/His |
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| Human | CENPO-3143HF | Recombinant Full Length Human CENPO Protein, GST-tagged | In Vitro Cell Free System | GST | 300 amino acids |
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| Zebrafish | CENPO-6038Z | Recombinant Zebrafish CENPO | Mammalian Cell | His |
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| Chicken | CENPO-2773C | Recombinant Chicken CENPO | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
CENPO involved in several pathways and played different roles in them. We selected most pathways CENPO participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell Cycle | CDKN1BA;PLK4;RBBP7;NUP35;MAPRE1;CDC26;TOP2A;TFDP2;KNTC1 |
| Cell Cycle, Mitotic | TOP2A;TCTN2;H3F3D;SKA1;LEMD3;CEP63;GORASP2;APITD1;CCP110 |
| Chromosome Maintenance | TERF2;DKC1;APITD1;MIS18BP1;CENPH;CENPW;TINF2;POT1A;CENPP |
| Deposition of new CENPA-containing nucleosomes at the centromere | CENPL;MIS18BP1;CENPH;CENPO;CENPI;NPM1;PANE1;HJURP;MIS18A |
| M Phase | AHCTF1;GORASP2;NCAPG;NDEL1;ERCC6L;SPDL1;SGOL1;SPC25;MASTL |
| Mitotic Anaphase | CDCA8;PANE1;SGOL2;AHCTF1;ANKLE2;CENPI;CENPP;INCENP;CENPC1 |
| Mitotic Metaphase and Anaphase | PMF1;PDS5B;RANGAP1B;SPC25;SGOL2;VRK2;KNTC1;CENPC1;LEMD3 |
| Mitotic Prometaphase | SPC25;NUF2;ZWINT;NDC80;PDS5B;CLIP1;CENPQ;SMC2;NDEL1 |
CENPO has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPO itself. We selected most functions CENPO had, and list some proteins which have the same functions with CENPO. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MBD1;S1PR3;CCDC117;RC3H2;EXOC8;UNG;LSM6;MPZL2B;ARHGDIA |
CENPO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPO here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPO.
CEP170P1; CENPP; NECAB2; FOS; RNF40; STRA13; PABPN1; PLXNB1; SEC22B
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