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CPT1B

  • Official Full Name

    carnitine palmitoyltransferase 1B (muscle)

  • Overview

    The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.
  • Synonyms

    CPT1B; carnitine palmitoyltransferase 1B (muscle); carnitine O-palmitoyltransferase 1, muscle isoform; CPT1 M; M CPT1; carnitine palmitoyltransferase I-like protein; carnitine O-palmitoyltransferase I, mitochondrial muscle isoform; CPTI; CPT1M; MCPT1; CPT;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Sus scrofa (Pig)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CPT1B-1819H Recombinant Human CPT1B Protein, GST-tagged Wheat Germ GST
Human CPT1B-26102TH Recombinant Human CPT1B Wheat Germ N/A 100 amino acids
Human CPT1B-1455H Recombinant Human CPT1B protein, His & T7-tagged E.coli His/T7 Thr602~Ser772 (Accession # Q92523)
Human CPT1B-7299HCL Recombinant Human CPT1B 293 Cell Lysate HEK293 N/A
Human CPT1B-1799H Recombinant Human CPT1B Protein (Thr602-Ser772), N-His tagged E.coli N-His Thr602-Ser772
Mouse CPT1B-3866M Recombinant Mouse CPT1B Protein Mammalian Cell His
Mouse CPT1B-1947M Recombinant Mouse CPT1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CPT1B-1947M-B Recombinant Mouse CPT1B Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL25583BF Recombinant Full Length Bovine Carnitine O-Palmitoyltransferase 1, Muscle Isoform(Cpt1B) Protein, His-Tagged E.coli expression system His Full Length (1-771)
Cynomolgus Monkey CPT1B-420C Recombinant Cynomolgus CPT1B Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey CPT1B-168C Recombinant Cynomolgus Monkey CPT1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey CPT1B-168C-B Recombinant Cynomolgus Monkey CPT1B Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL36801HF Recombinant Full Length Human Carnitine O-Palmitoyltransferase 1, Muscle Isoform(Cpt1B) Protein, His-Tagged E.coli expression system His Full Length (1-772)
Mus musculus (Mouse) RFL10539MF Recombinant Full Length Mouse Carnitine O-Palmitoyltransferase 1, Muscle Isoform(Cpt1B) Protein, His-Tagged E.coli expression system His Full Length (1-772)
Rattus norvegicus (Rat) RFL19282RF Recombinant Full Length Rat Carnitine O-Palmitoyltransferase 1, Muscle Isoform(Cpt1B) Protein, His-Tagged E.coli expression system His Full Length (1-772)
Rhesus Macaque CPT1B-1011R Recombinant Rhesus monkey CPT1B Protein, His-tagged Mammalian Cell His
Rhesus Macaque CPT1B-836R-B Recombinant Rhesus Macaque CPT1B Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CPT1B-836R Recombinant Rhesus Macaque CPT1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Sus scrofa (Pig) RFL25952SF Recombinant Full Length Pig Carnitine O-Palmitoyltransferase 1, Muscle Isoform(Cpt1B) Protein, His-Tagged E.coli expression system His Full Length (1-772)
Zebrafish CPT1B-1474Z Recombinant Zebrafish CPT1B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CPT1B Related Articles

CPT1B involved in several pathways and played different roles in them. We selected most pathways CPT1B participated on our site, such as AMPK signaling, AMPK signaling pathway, Adipocytokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPT1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AMPK signalingELAVL1;CPT1A;EEF2;INS-IGF2;CAMKK2;EIF4EBP1;LOC729991;SLC2A4RG;ADRa1A
AMPK signaling pathwayPRKAA2;IGF1;RAB11B;CAMKK1;AKT2;LEPR;PPP2R1A;CREB5;PCK1
Adipocytokine signaling pathwayRXRG;ACSL4;CHUK;TNFRSF1A;PRKAG3;LEPB;MAPK8B;ACACB;CAMKK1A
FOXA2 and FOXA3 transcription factor networksDLK1;UCP2;FOXA1;CEBPA;CPT1A;KCNJ11;FOXF1;CPT1C;TTR
Fatty Acid Beta OxidationCPT2;CPT1A;CHKB;DECR1;CRAT;CPT1B;ECI1;SLC25A20
Fatty acid degradationALDH9A1A.1;HADHA;ACSL1A;ACADVL;ADH2-2;ACSL1B;ACADSB;ACAT1;CYP4A12A
Fatty acid metabolismACSL4A;PTPLAD1;PPT2;CPT1A;ACSL4B;ACSL3A;ACSL3B;HADHAB;PPT1
Fatty acid, triacylglycerol, and ketone body metabolismMED31;CCNC;DGAT1B;SREBF2;CYP7A1;ACOT11;MED29;HELZ2;TMEM195

CPT1B has several biochemical functions, for example, carnitine O-palmitoyltransferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CPT1B itself. We selected most functions CPT1B had, and list some proteins which have the same functions with CPT1B. You can find most of the proteins on our site.

Function Related Protein
carnitine O-palmitoyltransferase activityCPT1A;CPT1C;CPT1B;CPT2
protein bindingAGPS;BMP1;ADORA1;RAD9;KLHDC4;COIL;TOMM7;PRC1;OTX2

CPT1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPT1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CPT1B.

C2orf57

Gao, S; McMillan, RP; et al. Regulation of Substrate Oxidation Preferences in Muscle by the Peptide Hormone Adropin. DIABETES 63:3242-3252(2014).
Gomez-Gomez, E; Rios-Martinez, ME; et al. Carnitine Palmitoyltransferase 1B 531K Allele Carriers Sustain a Higher Respiratory Quotient after Aerobic Exercise, but beta 3-Adrenoceptor 64R Allele Does Not Affect Lipolysis: A Human Model. PLOS ONE 9:-(2014).
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