Creative BioMart to Present at IMMUNOLOGY2024™|May 3-7, 2024|Booth #512 Learn More

CRB2

Official Full Name

crumbs homolog 2 (Drosophila)
Synonyms

CRB2;crumbs homolog 2 (Drosophila);18688;ENSG00000148204;RP11-230L22.2;9q33.3;FLJ16786, FLJ38464;crumbs homolog 2;crumbs homolog 2;crumbs-like protein 2;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	CRB2-3881M	Recombinant Mouse CRB2 Protein	Mammalian Cell	His	Inquiry
Mouse	CRB2-1960M-B	Recombinant Mouse CRB2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	CRB2-1960M	Recombinant Mouse CRB2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry

Involved Pathway
Protein Function
Interacting Protein
CRB2 Related Articles

CRB2 involved in several pathways and played different roles in them. We selected most pathways CRB2 participated on our site, such as Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Hippo signaling pathway	PPP2R2D;WNT16;ID1;PPP1CA;WNT7A;FZD10;WNT2B;PRKCI;TGFB1

CRB2 has several biochemical functions, for example, contributes_to aspartic-type endopeptidase inhibitor activity, calcium ion binding, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRB2 itself. We selected most functions CRB2 had, and list some proteins which have the same functions with CRB2. You can find most of the proteins on our site.

Function	Related Protein
contributes_to aspartic-type endopeptidase inhibitor activity
calcium ion binding	MYL9;EFCAB3;PCDH1A6;SYTL3;CRB1;PCDH11Y;SCGN;RASGRP3;SYT15
enzyme binding	ECM1;TSPAN33;C6orf211;PRKCH;USF1;HNRNPUL1;CYP2C8;LAMP2;NPM2

CRB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRB2.

Ebarasi, L; Ashraf, S; et al. Defects of CRB2 Cause Steroid-Resistant Nephrotic Syndrome. AMERICAN JOURNAL OF HUMAN GENETICS 96:153-161(2015).

Slavotinek, A; Kaylor, J; et al. CRB2 Mutations Produce a Phenotype Resembling Congenital Nephrosis, Finnish Type, with Cerebral Ventriculomegaly and Raised Alpha-Fetoprotein. AMERICAN JOURNAL OF HUMAN GENETICS 96:162-169(2015).