CD63
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Official Full Name
CD63 molecule
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Overview
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012] -
Synonyms
CD63; CD63 molecule; MLA1; ME491; LAMP-3; OMA81H; TSPAN30; CD63 antigen; tspan-30; granulophysin; tetraspanin-30; melanoma-associated antigen MLA1; CD63 antigen (melanoma 1 antigen); melanoma-associated antigen ME491; ocular melanoma-associated antigen; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Cynomolgus
- Cynomolgus Monkey
- Felis catus (Cat) (Felis silvestris catus)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Oryctolagus cuniculus (Rabbit)
- Pig
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- Human Cells
- In Vitro Cell Free System
- In vitro E. coli expression system
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- C
- His
- DYKDDDDK
- Fc
- Flag
- GST
- His (Fc)
- Avi
- His|GST
- His|SUMOstar
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CD63 Related Articles
- CD63 Related Research Area
CD63 involved in several pathways and played different roles in them. We selected most pathways CD63 participated on our site, such as Lysosome, Proteoglycans in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD63 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Lysosome | SLC11A2;GNSA;AP1S2;AP1S3B;CTSW;MCOLN1;NPC2;ATP6V0CA;CTSSA |
Proteoglycans in cancer | WNT7A;ESR1;PTK2;TLR4;CAMK2A;PLCG2;CAV3;SDC4;FZD2 |
CD63 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD63 itself. We selected most functions CD63 had, and list some proteins which have the same functions with CD63. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | TFIP11;TBC1D7;VAV2;CA4;DOK4;NKX3;CTNNA2;ENTPD3;VRK1 |
CD63 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD63 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD63.
env; TIMP1; LMP1; ITGB1; SRC; Ptpra; Enam; Ambn; q6krg0_bacan; Amelx
- Q&As
- Reviews
Q&As (7)
Ask a questionIt is associated with cancer progression, impacting cell migration and metastasis.
CD63 modulates immune responses, influencing antigen presentation and cell activation.
Targeting CD63 may offer therapeutic potential in cancer and immune-related diseases.
Its expression is regulated through transcriptional and post-translational mechanisms.
It helps in the sorting and transport of proteins within endosomes and lysosomes.
CD63 is a marker for exosomes, playing a role in their formation and function.
CD63 is involved in vesicular trafficking, cell adhesion, and signaling.
Customer Reviews (3)
Write a reviewConsistent and reliable protein.
Excellent yield, very pure.
Perfect for specific experiments.
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