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DLL3

  • Official Full Name

    delta-like 3 (Drosophila)

  • Overview

    This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms

    DLL3; delta-like 3 (Drosophila); SCDO1; delta-like protein 3; delta3; drosophila Delta homolog 3;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus macaque
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Yeast
  • Fc
  • FLAG
  • His
  • Avi
  • His (Fc)
  • His|SUMO
  • flag
  • SUMO
  • human|IgG1|Fc
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DLL3-31H Recombinant Human DLL3 protein, His-tagged HEK293 His Ala27-Leu492
Human DLL3-1189H Recombinant Human DLL3 Protein, His-SUMO-tagged E.coli His/SUMO
Human DLL3-856H Recombinant Human DLL3 Protein, FLAG-tagged HEK293 FLAG aa 27-466
Human DLL3-30H Recombinant Human DLL3 protein, Fc-tagged HEK293 human/IgG1/Fc Ala27-Leu492
Human DLL3-1719H Recombinant Human DLL3 Protein (27-492 aa), His-tagged Yeast His 27-492 aa
Human DLL3-4885H Recombinant Human DLL3 protein, His-SUMO-tagged E.coli His-SUMO 27-492aa
Human DLL3-965H Recombinant Human DLL3 Protein, His-flag-tagged HEK293 His-flag Ala27-Arg491
Human DLL3-1119H Recombinant Human DLL3 protein, His-SUMO-tagged E.coli His-SUMO 383-492aa
Human DLL3-1031H Active Recombinant Human DLL3 protein, His-tagged HEK293 His Ala27-Leu492
Human DLL3-1348H Recombinant Human DLL3 Protein, His-tagged E.coli N-His Ala27-Leu492
Mouse Dll3-32M Recombinant Mouse Dll3 protein, Fc-tagged HEK293 Fc
Mouse DLL3-4631M Active Recombinant Mouse DLL3 protein, His-tagged HEK293 His Ala25-Arg488
Mouse DLL3-4632M Recombinant Mouse DLL3 protein, His-tagged CHO His Ala 25 - Arg 488
Rat DLL3-1888R Recombinant Rat DLL3 Protein Mammalian Cell His
Rat DLL3-1547R Recombinant Rat DLL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DLL3-1547R-B Recombinant Rat DLL3 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus DLL3-2127C Active Recombinant Cynomolgus DLL3 protein, His-tagged HEK293 His Ala 27 - Arg 490
Cynomolgus DLL3-1870C Active Recombinant Cynomolgus DLL3 protein, His & Avi-tagged HEK293 His & Avi Ala 27 - Arg 488
Mus musculus (Mouse) RFL33772MF Recombinant Full Length Mouse Delta-Like Protein 3(Dll3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (33-592)
Rattus norvegicus (Rat) RFL36004RF Recombinant Full Length Rat Delta-Like Protein 3(Dll3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (33-589)
Rhesus macaque DLL3-171R Recombinant Rhesus macaque DLL3 protein, His-tagged HEK293 His It contains Ala27-Arg490.
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DLL3 Related Research Area

DLL3 involved in several pathways and played different roles in them. We selected most pathways DLL3 participated on our site, such as Neural Crest Differentiation, Notch Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neural Crest DifferentiationDMBX1;TCF4;HEY2;CDH7;MBP;ZIC1;CDH6;TBX6;MIA
Notch Signaling PathwayCTBP2;JAG1A;ADAM12;MFAP2;DTX2;JAG1B;CTBP1;NOTCH4;MARK2

DLL3 has several biochemical functions, for example, Notch binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLL3 itself. We selected most functions DLL3 had, and list some proteins which have the same functions with DLL3. You can find most of the proteins on our site.

Function Related Protein
Notch bindingNOTCH1;JAG1A;DNER;NOTCH4;C8orf4;AAK1;JAG1;HIF1AN;DLL3

DLL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLL3.

  • Q&As
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