EDNRA
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Official Full Name
endothelin receptor type A
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Overview
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] -
Synonyms
EDNRA; endothelin receptor type A; ETA; ET-A; ETAR; ETRA; ETA-R; hET-AR; endothelin-1 receptor; G protein-coupled receptor; endothelin receptor subtype A; endothelin-1-specific receptor;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Bos taurus (Bovine)
- Canis lupus familiaris (Dog) (Canis familiaris)
- Chicken
- Human
- Mouse
- Mus musculus (Mouse)
- Ovis aries (Sheep)
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Sus scrofa (Pig)
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- In vitro E. coli expression system
- Mammalian Cell
- Wheat Germ
- Yeast
- GST
- His
- His (Fc)
- Avi
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | EDNRA-764H | Active Recombinant Human EDNRA Full Length Transmembrane protein(VLPs) | HEK293 | N/A | Asp 21 - Asn 427 | |
Human | EDNRA-3058H | Recombinant Human EDNRA Protein, GST-tagged | Wheat Germ | GST | ||
Human | EDNRA-28562TH | Recombinant Human EDNRA | Wheat Germ | N/A | 63 amino acids | |
Human | EDNRA-6718HCL | Recombinant Human EDNRA 293 Cell Lysate | HEK293 | N/A | ||
Human | EDNRA-5392H | Recombinant Human EDNRA protein, His-tagged | Yeast | His | 21-80aa | |
Human | EDNRA-2371H | Recombinant Human EDNRA Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | His | 21–427aa | |
Human | EDNRA-6775HF | Recombinant Full Length Human EDNRA Protein | In Vitro Cell Free System | was amino acids | ||
Human | EDNRA-22H | Recombinant Human EDNRA Protein | Wheat Germ | N/A | ||
Human | EDNRA-1405H | Recombinant Human EDNRA Protein, His-tagged | E.coli | N-His | Asp21-Lys80 | |
Human | EDNRA-4202HF | Recombinant Full Length Human EDNRA Protein, GST-tagged | In Vitro Cell Free System | GST | 427 amino acids | |
Mouse | EDNRA-4994M | Recombinant Mouse EDNRA Protein | Mammalian Cell | His | ||
Mouse | EDNRA-2641M | Recombinant Mouse EDNRA Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | EDNRA-2641M-B | Recombinant Mouse EDNRA Protein Pre-coupled Magnetic Beads | HEK293 | |||
Bos taurus (Bovine) | RFL2534BF | Recombinant Full Length Bovine Endothelin-1 Receptor(Ednra) Protein, His-Tagged | E.coli expression system | His | Full Length (21-427) | |
Canis lupus familiaris (Dog) (Canis familiaris) | RFL7029CF | Recombinant Full Length Dog Endothelin-1 Receptor(Ednra) Protein, His-Tagged | E.coli expression system | His | Full Length (21-426) | |
Mus musculus (Mouse) | RFL27599MF | Recombinant Full Length Mouse Endothelin-1 Receptor(Ednra) Protein, His-Tagged | E.coli expression system | His | Full Length (21-427) | |
Ovis aries (Sheep) | RFL7142OF | Recombinant Full Length Sheep Endothelin-1 Receptor(Ednra) Protein, His-Tagged | E.coli expression system | His | Full Length (21-427) | |
Rattus norvegicus (Rat) | RFL24996RF | Recombinant Full Length Rat Endothelin-1 Receptor(Ednra) Protein, His-Tagged | E.coli expression system | His | Full Length (21-426) | |
Rhesus Macaque | EDNRA-1380R | Recombinant Rhesus monkey EDNRA Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | EDNRA-1205R-B | Recombinant Rhesus Macaque EDNRA Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rhesus Macaque | EDNRA-1205R | Recombinant Rhesus Macaque EDNRA Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Sus scrofa (Pig) | RFL6245SF | Recombinant Full Length Pig Endothelin-1 Receptor(Ednra) Protein, His-Tagged | E.coli expression system | His | Full Length (21-427) | |
Chicken | EDNRA-5695C | Recombinant Chicken EDNRA | Mammalian Cell | His | ||
Kit-0914 | CYP2J2 Cyan Screening Kit | N/A | ||||
Kit-1229 | EDNRA CHO-K1 β-Arrestin GPCR Assay Kit | N/A |
- Involved Pathway
- Protein Function
- Interacting Protein
- EDNRA Related Gene Family
- EDNRA Related Research Area
EDNRA involved in several pathways and played different roles in them. We selected most pathways EDNRA participated on our site, such as Calcium signaling pathway, Class A/1 (Rhodopsin-like receptors), EGFR-dependent Endothelin signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with EDNRA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Calcium signaling pathway | PPP3CCA;SLC25A31;GNAQ;HTR5A;CACNA1D;ADRB2A;PLCG2;ITPKB;PLCG1 |
Class A/1 (Rhodopsin-like receptors) | LPAR1;HEBP1;GPR55A;ZFPM2B;GPR55;OPN1LW2;PROK1;OPN1MW2;GPR132B |
EGFR-dependent Endothelin signaling events | EDN1;EDNRA |
Endothelin | CNN1;CALCRL;MYL1;CALCA;EDNRA;EDNRB;EDN1;RAMP1;ECE1 |
Endothelins | EDN2;EDN1;CYSLTR1;COL1A2;EDNRA;EDN3;EDNRB;COL3A1 |
G alpha (q) signalling events | PROK1;CHRM1;ABHD6B;CYSLTR1;PRKCHB;AGTR1;UTS2;QRFP;CHRM3 |
GPCR downstream signaling | ABHD6B;OBSCN;OXGR1A.2;ADORA2A;PENKB;APLNR;ANXA1B;UTS2D;CCL27 |
GPCR ligand binding | GPR4;PNOC;NPFF;EMR1;GPRC6A;GPR37L1;OPN4A;S1PR3;RGR |
EDNRA has several biochemical functions, for example, endothelin receptor activity, phosphatidylinositol phospholipase C activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EDNRA itself. We selected most functions EDNRA had, and list some proteins which have the same functions with EDNRA. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
endothelin receptor activity | EDNRBA;EDNRB;EDNRAA;EDNRAB;EDNRA |
phosphatidylinositol phospholipase C activity | PLCE1;PLCL1;CCR5;PLCD4;PLCL2;PLCB1;PLCD3A;PLCB4;CCL5 |
protein binding | CCL7;EIF1AD;UNC13A;MYLK;NAE1;BCL2L11;NKG7;AGR2;ZNF423 |
EDNRA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EDNRA here. Most of them are supplied by our site. Hope this information will be useful for your research of EDNRA.
EDN1
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