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EEF1A2

Official Full Name

eukaryotic translation elongation factor 1 alpha 2
Overview

This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. [provided by RefSeq, Mar 2014]
Synonyms

EEF1A2; eukaryotic translation elongation factor 1 alpha 2; HS1; STN; EF1A; STNL; EEF1AL; EF-1-alpha-2; elongation factor 1-alpha 2; statin-S1; eukaryotic elongation factor 1 A-2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A
T7

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	EEF1A2-3061H	Recombinant Human EEF1A2, T7-tagged	E.coli	T7		Inquiry
Human	EEF1A2-12289H	Recombinant Human EEF1A2 protein, GST-tagged	E.coli	GST	109-463 aa	$319 / 25ug
Human	EEF1A2-3067H	Recombinant Human EEF1A2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	EEF1A2-242HCL	Recombinant Human EEF1A2 lysate	HEK293	N/A		Inquiry
Human	EEF1A2-4206HF	Recombinant Full Length Human EEF1A2 Protein, GST-tagged	In Vitro Cell Free System	GST	463 amino acids	Inquiry
Human	EEF1A2-12290H	Recombinant Human EEF1A2 protein, His-tagged	E.coli	His	Gly213~Lys463	Inquiry
Mouse	EEF1A2-4999M	Recombinant Mouse EEF1A2 Protein	Mammalian Cell	His		Inquiry
Mouse	EEF1A2-2646M	Recombinant Mouse EEF1A2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	EEF1A2-2646M-B	Recombinant Mouse EEF1A2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	EEF1A2-2014R	Recombinant Rat EEF1A2 Protein	Mammalian Cell	His		Inquiry
Rat	EEF1A2-1671R	Recombinant Rat EEF1A2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	EEF1A2-1671R-B	Recombinant Rat EEF1A2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	EEF1A2-515Z	Recombinant Zebrafish EEF1A2	Mammalian Cell	His		Inquiry
Chicken	EEF1A2-3258C	Recombinant Chicken EEF1A2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
EEF1A2 Related Articles

EEF1A2 involved in several pathways and played different roles in them. We selected most pathways EEF1A2 participated on our site, such as Eukaryotic Translation Elongation, Gene Expression, Legionellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EEF1A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Eukaryotic Translation Elongation	EEF1A1;RPL35;EEF1G;EEF2;EEF1A2;EEF1D;EEF1B2
Gene Expression	ZNF287;LSM6;ZNF668;ZNF624;QTRTD1;ZKSCAN3;GLS2B;HBXIP;ZNF37A
Legionellosis	HSPA1L;SAR1B;CASP7;EEF1G;HSPA8;APAF1;IL12A;ITGB2L;NLRC4
Metabolism of proteins	ADD1;SENP1;SLC25A13;CCT7;TIMM22;CST3;UBA2;ADAMTS5;TRAPPC9
RNA transport	EIF3B;NXT2;NUP54;RPP14;EIF2B1;NUP188;RPP25;PABPC4;NUP133
Translation	EEF1A2;EIF5;APEH;EIF2B1;EEF1B2;EEF1D;EEF1G
Translation Factors	EEF1G;EIF1;EIF2B1;EEF1A2;EEF2B;PAIP1;EEF1B2;EIF4EBP2;EEF1D

EEF1A2 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EEF1A2 itself. We selected most functions EEF1A2 had, and list some proteins which have the same functions with EEF1A2. You can find most of the proteins on our site.

Function	Related Protein
GTP binding	RERGL;TRIM23;TRIM66;RAB42;GIMAP6;LRRK1;GNAV1;GBP4;EHD2B
GTPase activity	RAB14L;RAP1B;GNGT2;SAR1B;RABL2;TUBAL3;LGALS6;RAB33A;RAB18A
protein binding	NAPA;CAMLG;GJB6;SNAP29;SLC30A8;ZFPM2A;TERF2IP;SNX10;CASP9
protein kinase binding	CCNE1;CACNB2;PRKAG1;SLC12A7;APC;DNM1;PRC1;PLK1;PARP1
translation elongation factor activity	EEF1A1L2;EEF1D;EIF5A;EEF1DB;TUFM;TSFM;EEFSEC;EEF1DA;EEF2
translation factor activity, RNA binding	EIF1AX;CPEB1B;EIF4G3;GTF2H3;CPEB2;EEF2K;EIF1;GTF2H2;EIF4H

EEF1A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EEF1A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EEF1A2.

ABTB1; NFKB2; CHUK; TNFRSF1B; EEF1B2; VARS; EEF1D; MAP3K8; NFKB2; RELA; TRAF2; MAP3K1; TRADD; LRRK2; MAP3K3; TAB2; TRAF6; RIPK3

Chen, CY; Fang, HY; et al. Sumoylation of eukaryotic elongation factor 2 is vital for protein stability and anti-apoptotic activity in lung adenocarcinoma cells. CANCER SCIENCE 102:1582-1589(2011).

Piazzi, M; Bavelloni, A; et al. eEF1A Phosphorylation in the Nucleus of Insulin-stimulated C2C12 Myoblasts SER53 IS A NOVEL SUBSTRATE FOR PROTEIN KINASE C beta I. MOLECULAR & CELLULAR PROTEOMICS 9:-(2010).