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EFTUD2

Official Full Name

elongation factor Tu GTP binding domain containing 2
Overview

116 kDa U5 small nuclear ribonucleoprotein component is a protein that in humans is encoded by the EFTUD2 gene.
Synonyms

EFTUD2; elongation factor Tu GTP binding domain containing 2; 116 kDa U5 small nuclear ribonucleoprotein component; Snrp116; Snu114; U5 snRNP specific protein; 116 kD; U5 116KD; hSNU114; U5-116 kDa; SNU114 homolog; U5 snRNP specific protein, 116 kD; U5 sn;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Chicken
Human
Mouse
Zebrafish

Source

HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	EFTUD2-3110H	Recombinant Human EFTUD2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	EFTUD2-6698HCL	Recombinant Human EFTUD2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	EFTUD2-559H	Recombinant Human EFTUD2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	EFTUD2-4252HF	Recombinant Full Length Human EFTUD2 Protein, GST-tagged	In Vitro Cell Free System	GST	972 amino acids	Inquiry
Mouse	Eftud2-2758M	Recombinant Mouse Eftud2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	EFTUD2-10802Z	Recombinant Zebrafish EFTUD2	Mammalian Cell	His		Inquiry
Chicken	EFTUD2-3147C	Recombinant Chicken EFTUD2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
EFTUD2 Related Articles

EFTUD2 involved in several pathways and played different roles in them. We selected most pathways EFTUD2 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with EFTUD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Spliceosome	PPIL1;CCDC12;SRSF2;PUF60A;HSP70;SRSF5A;ISY1;SRSF6;NHP2L1

EFTUD2 has several biochemical functions, for example, GTP binding, GTPase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EFTUD2 itself. We selected most functions EFTUD2 had, and list some proteins which have the same functions with EFTUD2. You can find most of the proteins on our site.

Function	Related Protein
GTP binding	RAB11BA;IIGP1;GIMAP1;GTPBP2;SEPT4;ARFIP2;RAB3DA;RAB42B;RAB6C
GTPase activity	GNAT1;RAB20;DNM2B;AGAP2;GNA11;ARF4;GNA13B;RIT2;MXA
poly(A) RNA binding	ELAC2;PCBP3;ETF1B;HIST1H1E;RP9;CFAP20;EXOSC8;DROSHA;H1FX
protein binding	KPNA4;FDX1L;LAT2;ZNF593;RBMX;ASCL3;TFDP2;SCMH1;PCBP2
NOT translation elongation factor activity	GFM2;EFTUD2

EFTUD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFTUD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFTUD2.

MYC; SNRNP40; SNW1; PRPF8; HSPB1; IK; SF3B4; DFFA; PTP4A3

Sato, N; Maeda, M; et al. Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells. CANCER MEDICINE 4:268-277(2015).

Gandomi, SK; Parra, M; et al. Array-CGH is an effective first-tier diagnostic test for EFTUD2-associated congenital mandibulofacial dysostosis with microcephaly. CLINICAL GENETICS 87:80-84(2015).