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EIF2B2

  • Official Full Name

    eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa

  • Overview

    This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation.
  • Synonyms

    EIF2B2; eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD); translation initiation factor eIF-2B subunit beta; EIF 2Bbeta; EIF2B; S20I15; S20III15; eIF-2B GDP-GTP exchang;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EIF2B2-3156H Recombinant Human EIF2B2 Protein, GST-tagged Wheat Germ GST
Human EIF2B2-1535H Recombinant Human EIF2B2, T7-tagged E.coli T7
Human EIF2B2-12354H Recombinant Human EIF2B2, GST-tagged E.coli GST 1-351a.a.
Human EIF2B2-334H Recombinant Human EIF2B2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human EIF2B2-540HCL Recombinant Human EIF2B2 cell lysate N/A
Human EIF2B2-1416H Recombinant Human EIF2B2 Protein, His-tagged E.coli N-His Glu145-Asn327
Human EIF2B2-2045H Recombinant Human EIF2B2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EIF2B2-4490HF Recombinant Full Length Human EIF2B2 Protein, GST-tagged In Vitro Cell Free System GST 351 amino acids
Mouse EIF2B2-5080M Recombinant Mouse EIF2B2 Protein Mammalian Cell His
Mouse Eif2b2-2773M Recombinant Mouse Eif2b2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse EIF2B2-2701M Recombinant Mouse EIF2B2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse EIF2B2-2701M-B Recombinant Mouse EIF2B2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Eif2b2-1415M Recombinant Mouse Eif2b2 Protein, His-tagged E.coli N-His Ser103-Leu351
Rhesus Macaque EIF2B2-1415R Recombinant Rhesus monkey EIF2B2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EIF2B2-1239R-B Recombinant Rhesus Macaque EIF2B2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EIF2B2-1239R Recombinant Rhesus Macaque EIF2B2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish EIF2B2-12158Z Recombinant Zebrafish EIF2B2 Mammalian Cell His
Chicken EIF2B2-1620C Recombinant Chicken EIF2B2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EIF2B2 Related Articles

EIF2B2 involved in several pathways and played different roles in them. We selected most pathways EIF2B2 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2B2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportUPF3B;PEAK1;EIF5;EIF4A1A;PABPC5;TPRB;EEF1A2;EIF3I;PABPC1

EIF2B2 has several biochemical functions, for example, ATP binding, GTP binding, NOT S-methyl-5-thioribose-1-phosphate isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2B2 itself. We selected most functions EIF2B2 had, and list some proteins which have the same functions with EIF2B2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingUBE2D1;DCLK1;HSPA12A;BAT1;TAOK2;CDK9;HSPA1B;PDK2;STK19
GTP bindingGTPBP1L;RAB15;RAB1BA;MTG1;GUCY1B3;RAP2AB;EIF5;GUCY1A3;RAB40C
NOT S-methyl-5-thioribose-1-phosphate isomerase activityEIF2B4;EIF2B2;EIF2B1;EIF2B3
contributes_to guanyl-nucleotide exchange factor activityEIF2B1;EIF2B3;ALS2;C7orf59;EIF2B4;LAMTOR1;HBXIP;LAMTOR3;LAMTOR2
protein bindingHSD17B12;TBK1;CTSL1;TRIP6;HIST1H4J;AP3M1;SPRR2E;CACNA1SB;TLX1
contributes_to translation initiation factor activityEIF3B;EIF2B3;EIF2B1;EIF3A;EIF3EA;EIF3BA;EIF3E;EIF3G;EIF3C

EIF2B2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2B2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2B2.

CSNK2A2; CCT3; C9orf72; pi3p; Srp72; NSS; RPL10; DCC; EPB41L3

Hata, Y; Kinoshita, K; et al. An autopsy case of infantile-onset vanishing white matter disease related to an EIF2B2 mutation (V85E) in a hemizygous region. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:3355-3362(2014).
Unal, O; Ozgen, B; et al. Vanishing White Matter With Hepatomegaly and Hypertriglyceridemia Attacks. JOURNAL OF CHILD NEUROLOGY 28:1509-1512(2013).
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