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ETV7

Official Full Name

ets variant 7
Overview

The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).
Synonyms

ETV7; ets variant 7; ets variant gene 7 (TEL2 oncogene); transcription factor ETV7; TEL 2; TEL2; TEL2 oncogene; TELB; ETS related protein Tel2; Tel related Ets factor; Transcription factor Tel 2; TREF; tel-related Ets factor; ETS-related protein Tel2; ETS translocation variant 7; Ets transcription factor TEL-2b; TEL-2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Mammalian cells
Wheat Germ

Tag

Flag
GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ETV7-3542H	Recombinant Human ETV7 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ETV7-6518HCL	Recombinant Human ETV7 293 Cell Lysate	HEK293	N/A		Inquiry
Human	ETV7-785HFL	Recombinant Full Length Human ETV7 Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	ETV7-4373HF	Recombinant Full Length Human ETV7 Protein, GST-tagged	In Vitro Cell Free System	GST	341 amino acids	Inquiry
Human	ETV7-875H	Recombinant Human ETV7 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	ETV7-875H-B	Recombinant Human ETV7 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	ETV7-5344Z	Recombinant Zebrafish ETV7	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ETV7 Related Articles

ETV7 involved in several pathways and played different roles in them. We selected most pathways ETV7 participated on our site, such as Dorso-ventral axis formation, Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with ETV7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Dorso-ventral axis formation	CPEB3;FMN2;KRAS;ETS1;CPEB2;EGFRA;PIWIL1;GRB2;PIWIL2
Transcriptional misregulation in cancer	IL-8;SUPT3H;FUT8;SIX1;BIRC3;TGFBR2;HHEX;MLF1;PBX1

ETV7 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ETV7 itself. We selected most functions ETV7 had, and list some proteins which have the same functions with ETV7. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II regulatory region sequence-specific DNA binding	BARHL1B;ZSCAN20;CREBBP;ZNF792;ZNF583;CREB3L4;EGR1;GATA2B;TBX20
protein binding	SLC22A7;ATF7;PFTK1;SHE;SNX5;RADIL;PDE6H;NUPL1;RPH3A
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	SATB1;MNT;CHCHD3;BCL6;ETV7;ISX;E2F7;HOXD9;ZC3H8

ETV7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ETV7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ETV7.

VTN; LRPAP1; RICTOR; RPTOR

Bisio, A; Zamborszky, J; et al. Cooperative interactions between p53 and NF kappa B enhance cell plasticity. ONCOTARGET 5:12111-12125(2014).

Hang, BL; Sang, JJ; et al. Transcription analysis of the response of chicken bursa of Fabricius to avian leukosis virus subgroup J strain JS09GY3. VIRUS RESEARCH 188:8-14(2014).