EXOC1
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Official Full Name
exocyst complex component 1
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Overview
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described. -
Synonyms
EXOC1; exocyst complex component 1; SEC3 like 1 (S. cerevisiae) , SEC3L1; BM 102; FLJ10893; SEC3; Sec3p; BM-012; EXOC1_HUMAN; Exocyst complex component Sec3; SEC3 like 1; SEC3L1; SEC3-like 1; BM-102;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | EXOC1-12585H | Recombinant Human EXOC1, GST-tagged | E.coli | GST | C-term-350a.a. | |
Rhesus Macaque | EXOC1-1515R | Recombinant Rhesus monkey EXOC1 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | EXOC1-1340R-B | Recombinant Rhesus Macaque EXOC1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rhesus Macaque | EXOC1-1340R | Recombinant Rhesus Macaque EXOC1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Zebrafish | EXOC1-10000Z | Recombinant Zebrafish EXOC1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- EXOC1 Related Articles
EXOC1 involved in several pathways and played different roles in them. We selected most pathways EXOC1 participated on our site, such as Arf6 trafficking events, Assembly of the primary cilium, Cargo trafficking to the periciliary membrane, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXOC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Arf6 trafficking events | EXOC6;EXOC1;SPAG9;DNM2;SCAMP2;CTNND1;ADRB2;EDNRB;JUP |
Assembly of the primary cilium | DYNLL2A;TNPO1;MAPRE1B;ODF2;PROL1;UNC119.1;CEP57;CEP152;CLUAP1 |
Cargo trafficking to the periciliary membrane | RP2;CCT8;CCT5;EXOC8;CNGA2;PKD1;BBS9;RHOL;ARF4 |
Insulin Pathway | EXOC6;DOK1;GRB14;EXOC1;EXOC5;GRB10;EXOC3 |
Insulin processing | PCSK2;EXOC8;PCSK1;EXOC1;SLC30A5;SLC30A6;EXOC5;SLC30A8;CPE |
Membrane Trafficking | SH3D19;SNX9;TRAPPC5;ANKRD28;TRAPPC6B;GJA5;BLOC1S1;PPP6R1;COPB1 |
Metabolism of proteins | HDGF;MUC12;CMA1;EXOC6;IGFBP2B;MUCL1;ADAMTS1;MUC15;CHCHD4 |
Organelle biogenesis and maintenance | IFT52;MRPS34;IFT172;ARL3;CCDC123;RABL5;MRPL48;KIFAP3B;KIF17 |
EXOC1 has several biochemical functions, for example, GTP-Rho binding, phosphatidylinositol-4,5-bisphosphate binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EXOC1 itself. We selected most functions EXOC1 had, and list some proteins which have the same functions with EXOC1. You can find most of the proteins on our site.
Function | Related Protein |
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GTP-Rho binding | ROCK2B;CDC42EP2;EXOC1;TRIOBP;RTKN;ROCK1;RTKN2B;ROCK2A;CDC42EP5 |
phosphatidylinositol-4,5-bisphosphate binding | Apba1;SYT1;ALOX15;STXBP6L;SNX18;FRMPD4;FCHO2;RAG2;KCNJ1 |
protein binding | AP2M1;STAU1;SMG9;KIF6;KIF20B;ZC3HAV1;FGF12;C9orf142;FAM109A |
EXOC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXOC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXOC1.
WASH1; MYC; Kiaa0226; Atg14; SH3BP5; TRIO; SNAPIN; DST; GOLGA4; SPTAN1; COLEC12; ilvD; EXOC4; NUF2; TRIM9; CEP295; CCSER2; KIAA1551; DISC1
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