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FARP2

Official Full Name

FERM, RhoGEF and pleckstrin domain protein 2
Overview

FERM, RhoGEF and pleckstrin domain-containing protein 2 is a protein that in humans is encoded by the FARP2 gene.
Synonyms

FARP2; FERM, RhoGEF and pleckstrin domain protein 2; FERM, RhoGEF and pleckstrin domain-containing protein 2; FIR; FRG; KIAA0793; PLEKHC3; FARP 2; FERM; FGD1 related Cdc42 GEF; RhoGEF and pleckstrin domain protein 2; OTTHUMP00000200233; FGD1-related Cdc42-GEF; FERM domain including RhoGEF; PH domain-containing family C member 3; pleckstrin homology domain-containing family C member 3;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FARP2-3842H	Recombinant Human FARP2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FARP2-4713HF	Recombinant Full Length Human FARP2 Protein, GST-tagged	In Vitro Cell Free System	GST	647 amino acids	Inquiry
Mouse	FARP2-5681M	Recombinant Mouse FARP2 Protein	Mammalian Cell	His		Inquiry
Mouse	FARP2-3118M	Recombinant Mouse FARP2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	FARP2-3118M-B	Recombinant Mouse FARP2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
FARP2 Related Articles

FARP2 involved in several pathways and played different roles in them. We selected most pathways FARP2 participated on our site, such as Rap signaling pathway, Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with FARP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Rap signaling pathway	GNAO1;RAP1GAP;FGF1;ITGB3;ITGAM;CALM4;GNAI3;KLK1B4;FGF19
Adherens junction	CDC42L;SMAD2;Fert2;PARD3;INSRA;RHOAA;AASS;TGFBR1B;PTPRM

FARP2 has several biochemical functions, for example, Rac guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, cytoskeletal protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FARP2 itself. We selected most functions FARP2 had, and list some proteins which have the same functions with FARP2. You can find most of the proteins on our site.

Function	Related Protein
Rac guanyl-nucleotide exchange factor activity	ALS2;ARHGEF2;VAV3;DOCK2;VAV1;FARP2;FARP1;PREX2;SPATA13
Rho guanyl-nucleotide exchange factor activity	DOCK9;NET1;ITSN2;ALS2CL;OBSCN;PLEKHG4;FLJ20184;ABR;DNMBP
cytoskeletal protein binding	ACTN2;EPB4.1L4A;PACSIN1A;EPB41L4B;EZRB;MYLIP;PACSIN2;SLC8A1;PKD2
guanyl-nucleotide exchange factor activity	RASGRP1;ARHGEF18;DOCK11;CHRM4;P2RY12;VAV1;DOCK6;TAGAP;DIS3

FARP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FARP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FARP2.

Hmga2; Ywhah

DiTommaso, T; Jones, LK; et al. Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reverse Genetic Screen in the Mouse. PLOS GENETICS 10:-(2014).

Mlechkovich, G; Peng, SS; et al. Distinct Cytoplasmic Domains in Plexin-A4 Mediate Diverse Responses to Semaphorin 3A in Developing Mammalian Neurons. SCIENCE SIGNALING 7:-(2014).