FGL1
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Official Full Name
fibrinogen-like 1
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Overview
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. -
Synonyms
FGL1; fibrinogen-like 1; fibrinogen-like protein 1; HFREP 1; FGL 1; FGL1_HUMAN; Fibrinogen like 1; Fibrinogen like protein 1; Fibrinogen related protein 1; Hepassocin; Hepatocellular carcinoma related sequence; Hepatocyte derived fibrinogen related protein 1; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; HFREP1; HP 041; HP-041; HP041; LFIRE 1; LFIRE-1; LFIRE1; Liver fibrinogen related protein 1; Liver fibrinogen-related protein 1; MFIRE 1; MGC108569; MGC12455; MGC37822; OTTHUMP00000122468; OTTHUMP00000224774; OTTHUMP00000224775; OTTHUMP00000224776; OTTHUMP00000224916; hepatocellular carcinoma-related sequence; hepatocyte-derived fibrinogen-related;
- Recombinant Proteins
- Cell & Tissue Lysates
- GMP Proteins
- Protein Pre-coupled Magnetic Beads
- Cattle
- Chicken
- Cynomolgus
- Cynomolgus / Rhesus macaque
- Human
- Mouse
- Rat
- Baculovirus-Insect Cells
- E. coli
- E.coli
- HEK293
- HEK293F
- HEK293T
- Human Cell
- In Vitro Cell Free System
- Insect Cells
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Avi
- Fc
- His
- C
- 6His
- Fc\Avi
- Flag
- GST
- hFc
- Myc
- HIgG1 Fc
- HIgG1|Fc|Avi
- His (Fc)
- His\Avi
- His|GST
- His|S
- mFc
- MIgG2a Fc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
FGL1 involved in several pathways and played different roles in them. We selected most pathways FGL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FGL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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FGL1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FGL1 itself. We selected most functions FGL1 had, and list some proteins which have the same functions with FGL1. You can find most of the proteins on our site.
Function | Related Protein |
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FGL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGL1.
BCL2L11; q9wmx2-pro_0000037550
- Q&As
- Reviews
Q&As (6)
Ask a questionThere are still some challenges in the study of FGL1 recombinant protein, such as the need to better understand its structure and function relationship, and develop more effective drugs or treatments. In addition, due to the complexity and individual differences of tumor diseases, the therapeutic strategy against FGL1 recombinant protein also needs to be adjusted and optimized according to individual conditions.
Animal models carrying human mutant genes can be constructed using transgenic or gene editing technology to study the role and disease mechanism of FGL1 recombinant protein in vivo. These animal models can be used to study the effects of FGL1 recombinant protein on tumor growth and metastasis, among other things.
The function of FGL1 recombinant protein can be studied by gene knockout, transgenesis, protein interaction and other techniques.
FGL1 recombinant protein can interact with other proteins, such as cell surface receptors such as integrins, and participate in cell adhesion and migration processes.
In the experiment, the FGL1 gene can be introduced into the expression vector by gene cloning technology, and then the FGL1 recombinant protein can be expressed in Escherichia coli or eukaryotic cells.
The expression level of FGL1 recombinant protein can be detected by immunohistochemistry, immunofluorescence staining, western blotting, etc.
Customer Reviews (3)
Write a reviewFGL1 exhibits excellent stability and reproducibility under specific experimental conditions.
This protein has good stability and is suitable for long-term storage and use.
FGL1 protein has a long shelf life, which facilitates the continuity of subsequent experiments.
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