GAPDHS
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Official Full Name
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
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Overview
This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. -
Synonyms
GAPDHS; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; GAPDS; glyceraldehyde-3-phosphate dehydrogenase, testis-specific; GAPD2; GAPDH 2; spermatogenic glyceraldehyde-3-phosphate dehydrogenase; spermatogenic cell-specific glyceraldehyde 3-phospha;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Cynomolgus Monkey
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- GAPDHS Related Articles
- GAPDHS Related Research Area
GAPDHS involved in several pathways and played different roles in them. We selected most pathways GAPDHS participated on our site, such as Glycolysis / Gluconeogenesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GAPDHS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycolysis / Gluconeogenesis | ALDH7A1;ALDH9A1;ALDOC;LDHC;HK2;PKMA;GPIB;ALDOCB;G6PC |
| Metabolic pathways | ACSL3;UCKL1;TPI1B;UGT1A6B;udp;PKM2;CYP27A1;ATP6V1D;ATP6V0C |
GAPDHS has several biochemical functions, for example, NAD binding, NADP binding, glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GAPDHS itself. We selected most functions GAPDHS had, and list some proteins which have the same functions with GAPDHS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NAD binding | BDH2;TESCA;GAPDH;HSD3B4;HPGD;AOX3L1;IDH3G;GLYR1;MDH1 |
| NADP binding | SPR;IDH1;FMO2;NOS1;ASPDH;MTHFR;NOX5;GAPDH;ME1 |
| glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | GAPDHS;GAPDH |
| protein binding | SERPINF1;LRRC26;C10orf119;SYNJ2BP;SP2;PAX8;TACR3;CYS1;NAT8 |
GAPDHS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GAPDHS here. Most of them are supplied by our site. Hope this information will be useful for your research of GAPDHS.
NTHL1; SH3BP4; MDM2
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