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GDI1
Official Full Name
GDP dissociation inhibitor 1
Background
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family,;small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between;cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound;rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked;nonspecific mental retardation.
Synonyms
GDI1; GDP dissociation inhibitor 1; rab GDP dissociation inhibitor alpha; FLJ41411; GDI-1; GDIA_HUMAN; Guanosine diphosphate dissociation inhibitor 1; Mental retardation X-linked 41; Mental retardation X-linked 48; MRX41; MRX48; Oligophrenin 2; Oligophrenin-2; OPHN2; Protein XAP 4; Protein XAP-4; Protein XAP4; Rab GDI alpha; RABGD1A; RABGDIA; XAP 4; SMG p25A GDI