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GGH

  • Official Full Name

    gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)

  • Overview

    This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of;gamma-linked polyglutamates and glutamate.
  • Synonyms

    GGH; gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase); gamma-glutamyl hydrolase; gamma-Glu-X carboxypeptidase; GH;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GGH-25H Recombinant Human GGH Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human GGH-1399H Recombinant Human Gamma-Glutamyl Hydrolase (conjugase, folylpolygammaglutamyl hydrolase), His-tagged E.coli His
Human GGH-13241H Recombinant Human GGH, GST-tagged E.coli GST 23-318a.a.
Human GGH-5948HCL Recombinant Human GGH 293 Cell Lysate HEK293 N/A
Human GGH-4871H Recombinant Human GGH Protein, GST-tagged Wheat Germ GST
Human GGH-5231HF Recombinant Full Length Human GGH Protein, GST-tagged In Vitro Cell Free System GST 318 amino acids
Human GGH-549H Recombinant Human GGH Protein (Met1-Asp318), His-tagged HEK293 His Met1-Asp318
Mouse GGH-6326M Recombinant Mouse GGH Protein Mammalian Cell His
Mouse GGH-3543M Recombinant Mouse GGH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GGH-3543M-B Recombinant Mouse GGH Protein Pre-coupled Magnetic Beads HEK293
Mouse Ggh-3201M Recombinant Mouse Ggh Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat GGH-2518R Recombinant Rat GGH Protein Mammalian Cell His
Rat GGH-2174R Recombinant Rat GGH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GGH-2174R-B Recombinant Rat GGH Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GGH-1839R Recombinant Rhesus monkey GGH Protein, His-tagged Mammalian Cell His
Rhesus Macaque GGH-1660R-B Recombinant Rhesus Macaque GGH Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GGH-1660R Recombinant Rhesus Macaque GGH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish GGH-12509Z Recombinant Zebrafish GGH Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GGH Related Articles

GGH involved in several pathways and played different roles in them. We selected most pathways GGH participated on our site, such as Folate biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Folate biosynthesisMOCS1;GCH2;DHFR;ALPPL2;SPRA;FPGS;SPR;ALPI;ALPP

GGH has several biochemical functions, for example, exopeptidase activity, gamma-glutamyl-peptidase activity, omega peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GGH itself. We selected most functions GGH had, and list some proteins which have the same functions with GGH. You can find most of the proteins on our site.

Function Related Protein
exopeptidase activityGGH;ACE;MME
gamma-glutamyl-peptidase activity
omega peptidase activityUSP13;JOSD2;UCHL1;UCHL5;JOSD1;ATXN3;ATXN3L;GGH;USP5

GGH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGH here. Most of them are supplied by our site. Hope this information will be useful for your research of GGH.

ATP6V1A; MAP1LC3B

Hoang, PTV; Ambroise, J; et al. Comparative pharmacogenetic analysis of risk polymorphisms in Caucasian and Vietnamese children with acute lymphoblastic leukemia: prediction of therapeutic outcome?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 79:429-440(2015).
Kim, SE; Hinoue, T; et al. gamma-Glutamyl hydrolase modulation significantly influences global and gene-specific DNA methylation and gene expression in human colon and breast cancer cells. GENES AND NUTRITION 10:-(2015).
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