GINS3
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Official Full Name
GINS complex subunit 3 (Psf3 homolog)
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Overview
This gene encodes a protein subunit of the GINS heterotetrameric complex, which is essential for the initiation of DNA replication and replisome progression in eukaryotes. Alternatively spliced transcript variants encoding distinct isoforms have been described. -
Synonyms
GINS3; GINS complex subunit 3 (Psf3 homolog); DNA replication complex GINS protein PSF3; FLJ13912; PSF3; GINS complex subunit 3; PSF3 homolog;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
GINS3 involved in several pathways and played different roles in them. We selected most pathways GINS3 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, DNA Replication, which may be useful for your reference. Also, other proteins which involved in the same pathway with GINS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell Cycle | ANAPC4;LIN37;RAD9A;CDC7;MIS12;SPC24;TRP53;USO1;HIST4H4 |
| Cell Cycle, Mitotic | NDEL1;CEP78;SPDL1;SGOL1;CEP63;NDE1;CEP76;DCTN1A;NIPBLB |
| DNA Replication | SSBP1;LIG1;PRIM2;MCM3L;RPA1;RPA4;MCM6L;POLE2;RFC4 |
| DNA strand elongation | GINS2;GINS4;GINS1;DNA2;GINS3 |
| S Phase | GINS4;GINS3;ESCO2;GINS1;ESCO1;GINS2;MYCA |
| Synthesis of DNA | GINS4;GINS3;GINS2;GINS1 |
| Unwinding of DNA | GINS2;GINS3;GINS4;GINS1 |
GINS3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GINS3 itself. We selected most functions GINS3 had, and list some proteins which have the same functions with GINS3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
GINS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GINS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GINS3.
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