GJC2
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Official Full Name
gap junction protein, gamma 2, 47kDa
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Overview
This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. -
Synonyms
GJC2; gap junction protein, gamma 2, 47kDa; gap junction protein, alpha 12, 47kDa , GJA12; gap junction gamma-2 protein; connexin 47; CX46.6; CX47; SPG44; B230382L12Rik; Connexin 46.6; Connexin-46.6; Connexin-47; Connexin46.6; Connexin47; CX 46.6; Cx 47; CXG2_HUMAN; Gap junction alpha 12 protein; Gap junction alpha-12 protein; Gap junction gamma 2 protein; Gap junction protein alpha 12 47kDa; Gap junction protein gamma 2 47kDa; GAP JUNCTION PROTEIN, 47-KD; gap junction protein, gamma 12, 47kDa; GJA 12; GJA12; GJC 2; HLD 2; HLD2; MGC105119; MGC130506; OTTHUMP00000037763; PMLDAR; LMPH1C;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Chicken
- Homo sapiens (Human)
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Mouse | GJC2-6380M | Recombinant Mouse GJC2 Protein | Mammalian Cell | His | ||
Mouse | GJC2-3577M | Recombinant Mouse GJC2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | GJC2-3577M-B | Recombinant Mouse GJC2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | GJC2-2556R | Recombinant Rat GJC2 Protein | Mammalian Cell | His | ||
Rat | GJC2-2212R | Recombinant Rat GJC2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | GJC2-2212R-B | Recombinant Rat GJC2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Bos taurus (Bovine) | RFL28596BF | Recombinant Full Length Bovine Gap Junction Gamma-2 Protein(Gjc2) Protein, His-Tagged | E.coli expression system | His | Full Length (1-429) | |
Homo sapiens (Human) | RFL5312HF | Recombinant Full Length Human Gap Junction Gamma-2 Protein(Gjc2) Protein, His-Tagged | E.coli expression system | His | Full Length (1-439) | |
Mus musculus (Mouse) | RFL1604MF | Recombinant Full Length Mouse Gap Junction Gamma-2 Protein(Gjc2) Protein, His-Tagged | E.coli expression system | His | Full Length (1-440) | |
Rattus norvegicus (Rat) | RFL36576RF | Recombinant Full Length Rat Gap Junction Gamma-2 Protein(Gjc2) Protein, His-Tagged | E.coli expression system | His | Full Length (1-440) | |
Chicken | GJC2-4399C | Recombinant Chicken GJC2 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- GJC2 Related Articles
GJC2 involved in several pathways and played different roles in them. We selected most pathways GJC2 participated on our site, such as Calcium Regulation in the Cardiac Cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Calcium Regulation in the Cardiac Cell | CX30.3;KCNJ3;ADRa1A;GJA4;ADRB2;RGS5B;CX27.5;GJB6;CASQ1 |
GJC2 has several biochemical functions, for example, gap junction channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GJC2 itself. We selected most functions GJC2 had, and list some proteins which have the same functions with GJC2. You can find most of the proteins on our site.
Function | Related Protein |
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gap junction channel activity | GJA1;GJC2;CX43;GJB2;GJA8;CX30.3;PANX2;CX23;GJB3 |
GJC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJC2.
Ybx3
- Q&As
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