GNG12
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Official Full Name
guanine nucleotide binding protein (G protein), gamma 12
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Synonyms
GNG12; guanine nucleotide binding protein (G protein), gamma 12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; G-protein gamma-12 subunit; Guanine nucleotide binding protein (G protein) gamma 12; Hypothetical protein DKFZp762E193; OTTHUMP00000011139;
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- GST
- His
- His (Fc)
- Avi
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- MYC
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- GNG12 Related Articles
GNG12 involved in several pathways and played different roles in them. We selected most pathways GNG12 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK signaling pathway | PAK2B;CACNA2D4;RAP1A;TAOK1;CACNB4A;MAPK4;PPM1BB;STMN1;PRKACBB |
| Ras signaling pathway | RASAL2;RAP1A;INS1;KSR1;CALML3;GNB2;PLA2G1B;PIK3CG;PAK3 |
| Chemokine signaling pathway | GNGT1;PIK3R1;CXCL11;GNB1;CCL24;LYN;RAF1;PLCB2;CCR7 |
| PIK-Akt signaling pathway | Il2;ANGPT1;PHLPP2;RPS6KB1;CCNE2;IFNA1;EPOR;GNG5;PKN3 |
| Circadian entrainment | PLCB4;AKR1C1;MTNR1A;GNG4;PRKCG;GNAI1;KCNJ3;PRKACB;RYR1 |
| Retrograde endocannabinoid signaling | GNG4;RIMS1;GABRA2;ITPR3;GABRQ;GNAI2;GNG8;GNG13;GNG3 |
| Glutamatergic synapse | GRM4;GNG12;SLC38A1;HOMER2;GRM8;GRIK4;PPP3CC;PPP3CB;PLCB1 |
| Cholinergic synapse | Adcy4;PRKACA;PRKACG;AKR1C1;CAMK4;GNAQ;CAMK2G;SLC5A7;PLCB4 |
| Serotonergic synapse | PLCB4;CYP2C70;BRAF;MAPK1;ALOX12B;MAP2K1;NRAS;HTR2A;HTR7 |
| GABAergic synapse | GNAI2;SLC12A5;GABRB1;PRKCG;GNGT1;PRKCB;GNG4;GABBR1;GABRD |
| Dopaminergic synapse | DRD4;CREB3L3;CALM1;PRKACB;GNAI2;GNAS;KIF5A;DRD3;MAOB |
| Regulation of actin cytoskeleton | FGF1A;RAF1B;WAS;DIAPH3;FGF5;PIK3R3B;SSH2;RAF1;ITGB1A |
| Alcoholism | HIST1H3I;HIST1H2BD;H3F3B;CAMK4;HDAC10;CALM1;HDAC6;GNG5;GNG8 |
| Pathways in cancer | WNT9A;BIRC8;RXRA;RAC3;PLCG1;VHL;ITGAV;HDAC2;IKBKG |
GNG12 has several biochemical functions, for example, PDZ domain binding, phosphate ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG12 itself. We selected most functions GNG12 had, and list some proteins which have the same functions with GNG12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| PDZ domain binding | ATP2B2;TGFBR3;PROSAPIP1;USHBP1;KCNJ4;NSF;FZD8;GNG5;PTENA |
| phosphate ion binding | ADSSL1;CHST14;G6PC;PNP;GNG12;RELA;SH2B3;OTC;RPH3A |
| protein binding | SMPD1;BAIAP2;PPEF1;NFKB2;CTR9;PGM1;EPHA7;NUB1;TAF6L |
| signal transducer activity | CXCR2;TAS2R124;MTNR1BA;TAAR12A;GNA11B;OLFR867;OLFR688;CBLB;OLFCQ19 |
GNG12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG12 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG12.
FHL2; Cbx1; EIF4A2; Trim69; Poc1b; Mau2; RIPK3; FLNA; MYH9; Bmpr1a; BLK; Gnb1; Myh10; Kctd5; Ppp2r2d
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