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GPR4

  • Official Full Name

    G protein-coupled receptor 4

  • Overview

    G-protein coupled receptor 4 is a protein that in humans is encoded by the GPR4 gene.
  • Synonyms

    GPR4; G protein-coupled receptor 4; G-protein coupled receptor 4; G-protein coupled receptor 19;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Sus scrofa (Pig)
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GPR4-13476H Recombinant Human GPR4, GST-tagged E.coli GST 248-362a.a.
Human GPR4-5243H Recombinant Human GPR4 Protein, GST-tagged Wheat Germ GST
Human GPR4-5584HF Recombinant Full Length Human GPR4 Protein In Vitro Cell Free System 476 amino acids
Human GPR4-5242H Recombinant Human GPR4 Protein Wheat Germ N/A
Human GPR4-5585HF Recombinant Full Length Human GPR4 Protein, GST-tagged In Vitro Cell Free System GST 362 amino acids
Mouse GPR4-7188M Recombinant Mouse GPR4 Protein Mammalian Cell His
Mouse GPR4-3879M-B Recombinant Mouse GPR4 Protein Pre-coupled Magnetic Beads HEK293
Mouse GPR4-3879M Recombinant Mouse GPR4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GPR4-2667R Recombinant Rat GPR4 Protein Mammalian Cell His
Rat GPR4-2321R-B Recombinant Rat GPR4 Protein Pre-coupled Magnetic Beads HEK293
Rat GPR4-2321R Recombinant Rat GPR4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL21193BF Recombinant Full Length Bovine G-Protein Coupled Receptor 4(Gpr4) Protein, His-Tagged E.coli expression system His Full Length (1-362)
Homo sapiens (Human) RFL32418HF Recombinant Full Length Human G-Protein Coupled Receptor 4(Gpr4) Protein, His-Tagged E.coli expression system His Full Length (1-362)
Mus musculus (Mouse) RFL31298MF Recombinant Full Length Mouse G-Protein Coupled Receptor 4(Gpr4) Protein, His-Tagged E.coli expression system His Full Length (1-365)
Sus scrofa (Pig) RFL29157SF Recombinant Full Length Pig G-Protein Coupled Receptor 4(Gpr4) Protein, His-Tagged E.coli expression system His Full Length (1-362)
Kit-1316 GPR4 CHO-K1 β-Arrestin Orphan GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GPR4 Related Articles

GPR4 involved in several pathways and played different roles in them. We selected most pathways GPR4 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (q) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)GPR31B;AGTR1;GPR77;EDN1;RLN3A;NMBB;ADRa1A;GPR4;ADRA1D
G alpha (q) signalling eventsMLN;OPN4;QRFP;FPR-RS4;LPAR2A;OPN4A;GCGB;CHRM1;PMCH
GPCR downstream signalingEDNRA;ANXA1C;CALCRL;FGD2;GPRC6A;ADM2;ABHD6B;FPR-RS6;OXTRL
GPCR ligand bindingGNB5B;SSTR3;GNB5A;EDN2;GPBAR1;OPN4.1;RLN3A;NPFFR2;CXCR6
GPCRs, Class A Rhodopsin-likeNPFFR2;OPN1SW;CMKLR1;GPR18;OR3A4P;GPR31;FFAR3;GPR85;CCR3
Gastrin-CREB signalling pathway via PKC and MAPKCASR;QRFPR;ANXA1A;OPN4;TAE1;KISS1;NMU;GPR4;GPR132
Signal TransductionOR2AP1;OR4D2;TAX1BP1;OXGR1A.1;ARHGAP12B;ARHGAP19;GDI1;GPR68;MYO9B
Signaling by GPCRXK;UTS2;EMR1;PPY;TAS2R16;PNOCB;NTS;GPR37L1;TAAR1

GPR4 has several biochemical functions, for example, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR4 itself. We selected most functions GPR4 had, and list some proteins which have the same functions with GPR4. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityHTR2CL1;MRGPRA8;OR10A5;LPAR5B;GPR171;OLFR10;OPN5;ADORA2AB;OLFR495

GPR4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR4.

Mochimaru, Y; Azuma, M; et al. Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebra fish. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 457:493-499(2015).
Lu, ZY; Gui, HB; et al. Short-chain fatty acids and acidic pH upregulate UT-B, GPR41, and GPR4 in rumen epithelial cells of goats. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 308:R283-R293(2015).
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