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HSF4
Official Full Name
heat shock transcription factor 4
Background
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses.HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
Synonyms
HSF4; heat shock transcription factor 4; heat shock factor protein 4; hHSF4; HSF 4; HSF4_HUMAN; HSTF 4; DNA binding protein; heat shock factor 4; binds heat shock DNA elements; ldis1; mHSF4