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IFNA21

  • Official Full Name

    interferon, alpha 21

  • Overview

    This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus.
  • Synonyms

    IFNA21; interferon, alpha 21; interferon alpha-21; IFN alphaI; leukocyte interferon protein; Interferon alpha F; LeIF F; MGC126687; MGC126689; IFN-alpha-21; interferon alpha-F; leIF-F; IFN-alphaI;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Spf Chicken Eggs
  • Yeast
  • His
  • His|GST
  • Myc
  • DDK
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IFNA21-77H Recombinant Human Interferon, Alpha 21 E.coli N/A
Human IFNA21-41H Recombinant Human Interferon, Alpha 21 E.coli N/A
Human IFNA21-140H Recombinant Human Interferon, Alpha 21 Spf Chicken Eggs N/A
Human IFNA21-5280HCL Recombinant Human IFNA21 293 Cell Lysate HEK293 N/A
Human IFNA21-6275H Recombinant Human IFNA21 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IFNA21-1424H Recombinant Human IFNA21 Protein (24-189 aa), His-tagged Yeast His 24-189 aa
Human IFNA21-617H Recombinant Human IFNA21 Protein, His/GST-tagged E.coli His/GST Asp25~Glu189
Human IFNA21-3100H Recombinant Human IFNA21 Protein (Asp25-Glu189), N-GST tagged E.coli N-GST Asp25-Glu189
Human IFNA21-3069H Recombinant Human IFNA21 protein, His-tagged E.coli His 24-189aa
Human IFNA21-076H Recombinant Human IFNA21 Protein E. coli
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IFNA21 Related Articles

IFNA21 involved in several pathways and played different roles in them. We selected most pathways IFNA21 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionCTF1;IL10RB;IL10RA;TNFRSF19;IL26;TNFRSF25;FLT3LG;CXCL2;TNFRSF1B
Regulation of autophagyIFNA7;IFNA16;IFNA5;ULK3;INS1;GABARAPL2;ATG4D;PRKAA2;IFNA14
PIK-Akt signaling pathwayPIK3R2;GYS2;ITGB7;GNG10;FGF6;RAF1;Il6ra;FGF20;FLT1
Toll-like receptor signaling pathwayIKBKB;TLR8;IRAK1;MAPK9;PIK3CG;MAP2K4A;IRF7;RAC1A;AKT3A
RIG-I-like receptor signaling pathwayMAP3K1;IL8L1;MAPK12B;TBKBP1;IFNA5;MAP3K7;CXCL10;MAVS;IFNE
Cytosolic DNA-sensing pathwayTMEM173;DDX58;ZBP1;IFNPHI3;NFKBIA;IFNA1;NFKB1;POLR3D;RIPK1L
Jak-STAT signaling pathwayPIK3R1;AOX3L1;IFNA2;IFNA3;M17;IL2RGB;IFNA6;PTPN6;IL20RA
Natural killer cell mediated cytotoxicityTNFRSF10C;TYROBP;NCR3;IFNA1;GZMB;IFNA16;HLA-E;RAET1D;ULBP3
TuberculosisNFYC;ITGB2;CALML3;CAMK2A;CALM1;HLA-DRB1;TLR2;IL6;IL1A
Hepatitis CLDLR;NR1H3;IFNA17;CLDN5;PIK3R5;SCARB1;PIK3R3;IFNA5;CLDN9
Hepatitis BTLR4;SMAD4;KRAS;YWHAZ;YWHAB;PIK3R2;MAP2K2;FAS;ATP6AP1
MeaslesIRAK4;SLAMF1;NFKBIA;IL2RB;PIK3CG;CCNE1;IL13;STAT5B;AKT2
Influenza AEIF2AK4;PIK3CD;IFNA2;TRIM25;DDX39B;HLA-DRB4;GSK3B;IFNA17;AKT2
Herpes simplex infectionDDX58;HCFC2;BMA1;IL12B;EIF2AK2;PPP1CAA;TAF5L;CLOCKA;SRSF5A
AutoiIFNA2;HLA-G;PRF1;CD80;TSHR;HLA-DRB4;IFNA1;IL5;HLA-DOA
ne thyroid diseaseHLA-A;IFNA5;IFNA16;CD40LG;HLA-DOB;HLA-DRA;HLA-DRB1;HLA-DPA1;IFNA4

IFNA21 has several biochemical functions, for example, cytokine activity, cytokine receptor binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA21 itself. We selected most functions IFNA21 had, and list some proteins which have the same functions with IFNA21. You can find most of the proteins on our site.

Function Related Protein
cytokine activityGM13287;CCL38A.5;RNF207B;AREG;IL36G;LFT1;INHBE;CCL38A.4;Il1f8
cytokine receptor bindingIFNA21;IL17B;IL17A;IFNPHI3;IL17A/F2;IFNPHI2;IFNPHI4;IFNPHI1;IL17A/F1
type I interferon receptor bindingIfnz;Ifna11;IFNA7;IFNA2;IFNA5;Gm13290;IFNA21;IFNK;IFNA10

IFNA21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNA21 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNA21.

Guo, YL; Gao, MC; et al. Molecular cloning and characterization of a novel bovine IFN-epsilon. GENE 558:25-30(2015).
Liu, R; Huang, DD; et al. Immunization with Recombinant SFTSV/NSs Protein Does Not Promote Virus Clearance in SFTSV-Infected C57BL/6J Mice. VIRAL IMMUNOLOGY 28:113-122(2015).
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