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Ifna

  • Official Full Name

    glycoprotein hormones, alpha polypeptide/chorionic gonadotropin, beta polypeptide

  • Overview

    Chorionic Gonadotropin (hCG) is a glycoprotein hormone which is normally produced by the placenta during pregnancy. After conception, the hCG concentration increases rapidly to reach a peak near the end of the first trimester. High concentrations are observed throughout pregnancy. After delivery, hCG levels fall rapidly and become undetectable after a few days. Structurally intact hCG molecules are composed of an alpha and a beta subunit. The alpha subunit is nearly identical to the alpha subunits of other glycoprotein hormones, such as Thyroid Stimulating Hormone (TSH), Luteinizing Hormone (LH), and Follicle Stimulating Hormone (FSH): The differences in the beta subunit of the respective hormones account for their biological specificity and immunochemical distinctiveness. Monoclonal antibodies recognizing unique sites on the beta chain of the β-hCG/hCG molecule are essential for differentiation between hCG and LH, FSH and TSH. Specific assays for beta-hCG permit the early detection of pregnancy. In addition to the elevated hCG levels during pregnancy, high concentrations of βhCG/hCG may be associated with neoplasms of trophoblastic and nontrophoblastic origin such as hydatiform mole, chorionepithelioma, embryonal cell carcinoma, seminoma and many others. Human type I interferons comprise a vast and growing group of IFN proteins. All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor (IFNAR) that consists of IFNAR1 and IFNAR2 chains. Homologous molecules to type I IFNs are found in many species, including all mammals, and some have been identified in birds, reptiles, amphibians and fish species. The IFN-α proteins are produced by leukocytes. They are mainly involved in innate immune response against viral infection. They come in 13 subtypes that are called IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21. These genes for these IFN-α molecules are found together in a cluster on chromosome 9. IFN-α is also made synthetically as medication. Types are: Pegylated interferon alfa-2a Pegylated interferon alfa-2b
  • Synonyms

    HCG/CGB; human chorionic gonadotropin/Chorionic Gonadotropin, Beta Polypeptide; interferon-alpha; IFNaA; IFN-a; interferon alpha-A; interferon alpha A; Ifna; interferon alpha;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Transfected Stable Cell Lines
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Canine
  • Chicken
  • Cotton Rat
  • Cynomolgus Monkey
  • Goat
  • Human
  • Mouse
  • Rabbit
  • Rat
  • Rhesus Macaque
  • Sheep
  • E.coli
  • HEK293
  • HEK293F
  • HEK293T
  • Mammalian Cell
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NCALD-27853TH Recombinant Human NCALD, His-tagged E.coli His 193 amino acids
Human NCALD-3955HCL Recombinant Human NCALD 293 Cell Lysate HEK293 N/A
Human NCALD-249H Recombinant Human NCALD Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human NCALD-2494H Recombinant Human NCALD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IFNA-145H Human Interferon alpha(rDNA derived) Reference standard N/A
Human NCALD-2806H Recombinant Human NCALD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NCALD-252H Recombinant Human NCALD Protein, His-tagged E.coli His
Human NCALD-3348H Recombinant Human NCALD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NCALD-4138H Recombinant Human NCALD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IFNA-144H Human Interferon alpha (leukocyte derived) Reference standard N/A
Human NCALD-1743H Recombinant Human NCALD protein, His & T7-tagged E.coli His/T7 Gly2~Phe193 (Accession # P61601)
Human NCALD-6238H Recombinant Human NCALD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NCALD-325H Recombinant Human NCALD protein, His-tagged E.coli His 192
Human NCALD-3263H Recombinant Human NCALD protein, GST-tagged E.coli GST 1-193aa
Mouse Ifna-485M Recombinant Mouse Ifna protein, His-tagged HEK293F His Cys24~Lys189
Mouse NCALD-10452M Recombinant Mouse NCALD Protein Mammalian Cell His
Mouse Ifna-189M Recombinant Murine Interferon Alpha E.coli N/A
Mouse IFNA-4440M-B Recombinant Mouse IFNA Protein Pre-coupled Magnetic Beads HEK293
Mouse Ncald-4301M Recombinant Mouse Ncald Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse IFNA-4440M Recombinant Mouse IFNA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NCALD-3914R Recombinant Rat NCALD Protein Mammalian Cell His
Rat IFNA-2650R Recombinant Rat IFNA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat IFNA-2650R-B Recombinant Rat IFNA Protein Pre-coupled Magnetic Beads HEK293
Rabbit IFNA-642R Recombinant Rabbit IFNA protein, His & GST-tagged E.coli His/GST Ser1~Val93
Rabbit IFNA-972R Recombinant Rabbit IFNA Protein, His-tagged E.coli N-His Ser1-Val93
Bovine IFN-a-62B Recombinant Bovine Interferon-Alpha Yeast N/A
Canine IFNa-41C Recombinant Canine IFN alpha Yeast N/A
Cotton Rat IFNA-389C Active Recombinant Cotton Rat IFNA E.coli N/A
Cynomolgus Monkey NCALD-727C Recombinant Cynomolgus NCALD Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey IFNA-358C Recombinant Cynomolgus Monkey IFNA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey IFNA-358C-B Recombinant Cynomolgus Monkey IFNA Protein Pre-coupled Magnetic Beads HEK293
Goat IFNA-4334G Recombinant Goat IFNA Protein Yeast N/A 127aa
Rhesus Macaque NCALD-2952R Recombinant Rhesus monkey NCALD Protein, His-tagged Mammalian Cell His
Rhesus Macaque IFNA-2024R Recombinant Rhesus Macaque IFNA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque IFNA-2024R-B Recombinant Rhesus Macaque IFNA Protein Pre-coupled Magnetic Beads HEK293
Sheep IFNa-1262S Recombinant Sheep IFNa protein, His-tagged HEK293 His Cys24~Pro195
Chicken IFNA-1127C Active Recombinant Chicken IFNA E.coli N/A
Chicken NCALD-6700C Recombinant Chicken NCALD Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Ifna Related Research Area
  • Ifna Related Signal Pathway

Ifna involved in several pathways and played different roles in them. We selected most pathways Ifna participated on our site, such as Type II interferon signaling (IFNG), which may be useful for your reference. Also, other proteins which involved in the same pathway with Ifna were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Type II interferon signaling (IFNG)Ifna;REG1A;IFI6;GBP1;IFIT2

Ifna has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Ifna itself. We selected most functions Ifna had, and list some proteins which have the same functions with Ifna. You can find most of the proteins on our site.

Function Related Protein

Ifna has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ifna here. Most of them are supplied by our site. Hope this information will be useful for your research of Ifna.

  • Q&As
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