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KCNG3

  • Official Full Name

    potassium voltage-gated channel, subfamily G, member 3

  • Overview

    Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms.
  • Synonyms

    KCNG3; potassium voltage-gated channel, subfamily G, member 3; potassium voltage-gated channel subfamily G member 3; Kv6.3; KCNG 3; KCNG3_HUMAN; KV10.1; Kv10.1a; Kv10.1b; OTTHUMP00000201478; OTTHUMP00000201479; Potassium voltage gated channel subfamily G member 3; Voltage gated potassium channel 6.3; Voltage gated potassium channel Kv10.1; Voltage gated potassium channel subunit Kv10.1; Voltage gated potassium channel subunit Kv6.3; Voltage gated potassium channel subunit Kv6.4; Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3; OTTHUMP00000158763; OTTHUMP00000158764; voltage-gated potassium channel 6.3; voltage-gated potassium channel Kv10.1; voltage-gated potassium channel subunit Kv6.4;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KCNG3-5062HCL Recombinant Human KCNG3 293 Cell Lysate HEK293 N/A
Mouse KCNG3-8496M Recombinant Mouse KCNG3 Protein Mammalian Cell His
Mouse KCNG3-4730M-B Recombinant Mouse KCNG3 Protein Pre-coupled Magnetic Beads HEK293
Mouse KCNG3-4730M Recombinant Mouse KCNG3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KCNG3-3181R Recombinant Rat KCNG3 Protein Mammalian Cell His
Rat KCNG3-2837R Recombinant Rat KCNG3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KCNG3-2837R-B Recombinant Rat KCNG3 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL9778HF Recombinant Full Length Human Potassium Voltage-Gated Channel Subfamily G Member 3(Kcng3) Protein, His-Tagged E.coli expression system His Full Length (1-436)
Mus musculus (Mouse) RFL27666MF Recombinant Full Length Mouse Potassium Voltage-Gated Channel Subfamily G Member 3(Kcng3) Protein, His-Tagged E.coli expression system His Full Length (1-433)
Rattus norvegicus (Rat) RFL360RF Recombinant Full Length Rat Potassium Voltage-Gated Channel Subfamily G Member 3(Kcng3) Protein, His-Tagged E.coli expression system His Full Length (1-433)
Rhesus Macaque KCNG3-2352R Recombinant Rhesus monkey KCNG3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque KCNG3-2173R-B Recombinant Rhesus Macaque KCNG3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque KCNG3-2173R Recombinant Rhesus Macaque KCNG3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KCNG3 Related Articles

KCNG3 involved in several pathways and played different roles in them. We selected most pathways KCNG3 participated on our site, such as Neuronal System, Potassium Channels, Voltage gated Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNG3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuronal SystemGRIP1;KCNS3;GJC1;KCNG3;KCNQ2A;KCNK13A;KCND2;KCNMB2;GJA10
Potassium ChannelsKCNH2;KCNJ1A.6;KCNH2A;KCNG4A;KCNH5A;KCNN2;KCNJ1A.1;KCNF1;KCNJ14
Voltage gated Potassium channelsKCNAB1;KCNB2;KCNF1;KCNH6A;KCNH5;KCNC1A;KCNAB2B;KCNA4;KCNF1A

KCNG3 has several biochemical functions, for example, delayed rectifier potassium channel activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNG3 itself. We selected most functions KCNG3 had, and list some proteins which have the same functions with KCNG3. You can find most of the proteins on our site.

Function Related Protein
delayed rectifier potassium channel activityKCNC2;KCNC1;KCNE1;KCNB1;KCNG4A;KCNC1B;KCNQ2A;KCNC4;KCNS2
protein bindingFRA10AC1;CUL4A;TLK2;NAT2;POLR2L;TBX18;FAM59A;ARFRP1;KCNK16

KCNG3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNG3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNG3.

MYC

Kaminsky, Z; Jones, I; et al. DNA methylation and expression of KCNQ3 in bipolar disorder. BIPOLAR DISORDERS 17:150-159(2015).
Hashimoto, R; Ohi, K; et al. The KCNH2 gene is associated with neurocognition and the risk of schizophrenia. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY 14:114-120(2013).
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