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Official Full Name
membrane-associated ring finger (C3HC4) 4
MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 220.127.116.11). MARCH enzymes add;ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport;between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them;to the endosomal compartment (Bartee et al., 2004 (PubMed 14722266)).
MARCH4; membrane-associated ring finger (C3HC4) 4; E3 ubiquitin-protein ligase MARCH4; KIAA1399; MARCH IV; RNF174; RING finger protein 174; membrane-associated RING-CH protein IV; membrane-associated RING finger protein 4; MARCH-IV