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MTUS1

Official Full Name

microtubule associated tumor suppressor 1
Overview

This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.
Synonyms

MTUS1; microtubule associated tumor suppressor 1; mitochondrial tumor suppressor 1; microtubule-associated tumor suppressor 1; AT2 receptor interacting protein; AT2R binding protein; ATBP; ATIP1; DKFZp586D1519; FLJ14295; KIAA1288; mitochondrial tumor suppressor gene 1; MP44; MTSG1; Angiotensin II type 2 receptor interacting protein; ATIP; DKFZp686F20243; Erythroid differentiation related; GK 1; GK1; MP 44; MTSG 1; MTUS 1; Transcription factor MTSG1; OTTHUMP00000224769; OTTHUMP00000224771; OTTHUMP00000224772; OTTHUMP00000224773; AT2 receptor-binding protein; AT2 receptor-interacting protein; erythroid differentiation-r;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
His|T7
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MTUS1-7965H	Recombinant Human MTUS1 protein, His & T7-tagged	E.coli	His/T7	Leu1018~Arg1270 (Accession # Q9ULD2)	Inquiry
Human	MTUS1-426HCL	Recombinant Human MTUS1 lysate	HEK293	N/A		Inquiry
Human	MTUS1-5741H	Recombinant Human MTUS1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MTUS1-5042H	Recombinant Human MTUS1 Protein (Met1031-Arg1270), N-His tagged	E.coli	N-His	Met1031-Arg1270	Inquiry
Human	MTUS1-6567HF	Recombinant Full Length Human MTUS1 Protein, GST-tagged	In Vitro Cell Free System	GST	240 amino acids	Inquiry
Mouse	MTUS1-10223M	Recombinant Mouse MTUS1 Protein	Mammalian Cell	His		Inquiry
Mouse	Mtus1-7966M	Recombinant Mouse Mtus1 protein, His & T7-tagged	E.coli	His/T7	Glu1020~Arg1210 (Accession # Q5HZI1)	Inquiry
Mouse	MTUS1-5799M-B	Recombinant Mouse MTUS1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	MTUS1-5799M	Recombinant Mouse MTUS1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	MTUS1-3820R	Recombinant Rat MTUS1 Protein	Mammalian Cell	His		Inquiry
Rat	Mtus1-7967R	Recombinant Rat Mtus1 protein, His & T7-tagged	E.coli	His/T7	Met1~Ala196 (Accession # Q6IMY1)	Inquiry
Rat	MTUS1-3479R	Recombinant Rat MTUS1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	MTUS1-3479R-B	Recombinant Rat MTUS1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
MTUS1 Related Articles

MTUS1 involved in several pathways and played different roles in them. We selected most pathways MTUS1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MTUS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

MTUS1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MTUS1 itself. We selected most functions MTUS1 had, and list some proteins which have the same functions with MTUS1. You can find most of the proteins on our site.

Function	Related Protein

MTUS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTUS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTUS1.

ORC4; HTT; pdaB

Boukhari, A; Alhosin, M; et al. CD47 Activation-induced UHRF1 Over-expression Is Associated with Silencing of Tumor Suppressor Gene p16(INK4A) in Glioblastoma Cells. ANTICANCER RESEARCH 35:149-157(2015).

Hosseini, H; Rajabibazl, M; et al. Inhibiting angiogenesis with human single-chain variable fragment antibody targeting VEGF. MICROVASCULAR RESEARCH 97:13-18(2015).