Creative BioMart to Present at IMMUNOLOGY2024™|May 3-7, 2024|Booth #512 Learn More

NFE2L3

Official Full Name

nuclear factor (erythroid-derived 2)-like 3
Overview

This gene encodes a member of the cap n collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.
Synonyms

NFE2L3; nuclear factor (erythroid-derived 2)-like 3; nuclear factor erythroid 2-related factor 3; Nrf3; erythroid derived 2; like 3; NF-E2-related factor 3; NF2L3_HUMAN; NFE2-related factor 3; Nuclear factor; nuclear factor, erythroid derived 2, like 3; nuclear factor-erythroid 2-related factor 3; nuclear factor-erythroid 2 p45-related factor 3;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NFE2L3-1277H	Recombinant Human NFE2L3, GST-tagged	E.coli	GST	347-694aa	$319 / 25ug
Human	NFE2L3-187H	Recombinant Human NFE2L3 Protien, His-tagged	E. coli	His	347-694 aa	$319 / 25ug
Human	NFE2L3-3386H	Recombinant Human NFE2L3 protein, His-tagged	E.coli	His	74-258 aa	$319 / 25ug
Zebrafish	NFE2L3-12433Z	Recombinant Zebrafish NFE2L3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

NFE2L3 involved in several pathways and played different roles in them. We selected most pathways NFE2L3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NFE2L3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

NFE2L3 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NFE2L3 itself. We selected most functions NFE2L3 had, and list some proteins which have the same functions with NFE2L3. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA binding	NFE2L3;SOX1;DDN;ETS2;PYDC3;EN1;MED1;GCM1;SP1
protein binding	CDKN2D;ADAMTSL5;PYCARD;HUWE1;NBN;VAC14;NMRK2;SETDB1;EFNB1
transcription coactivator activity	JUND;TAF9;TRIM24;JUNBA;ECD;ELF3;VGLL2;JMY;PIAS2
transcription factor activity, sequence-specific DNA binding	ARNT;Aff1;ZNF792;ZC3H8;SLC25A46;ZFP516;ATOH8;NR3C2;ZKSCAN14
transcription regulatory region sequence-specific DNA binding	MEF2AA;FOXJ1;PSPC1;MEF2CA;NONO;NR5A2;CRY2;CREB3L3;KDM3A
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	PRDM5;GATA3;TFAP2A;GZF1;MZF1;ZFP536;NFE2L3;FOXO1;NFIL3-6

NFE2L3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NFE2L3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NFE2L3.

MAFG; ATF4; NFE2