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OPRM1

  • Official Full Name

    opioid receptor, mu 1

  • Overview

    The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. The κ-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood.
  • Synonyms

    OPRK1; K-OR-1; Kappa type opioid receptor; Kappa-type opioid receptor; KOR 1; KOR; KOR-1; Opiate receptor kappa 1; OPRK 1; OPRK; OPRK_HUMAN; Oprk2; R21; opioid receptor, kappa 1; OTTHUMP00000226313; Opioid Receptor, kappa; OTTHUMP00000226316; kappa opioid receptor; Opiate receptor, kappa-1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Cavia porcellus (Guinea pig)
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • Macaca mulatta (Rhesus macaque)
  • Mouse
  • Mus musculus (Mouse)
  • Pan troglodytes (Chimpanzee)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
  • Sus scrofa (Pig)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In vitro E. coli expression system
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human OPRM1-295H Recombinant Human OPRM1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human OPRM1-1147HFL Recombinant Human OPRM1 protein, His&Flag-tagged HEK293 His&Flag 1-400 aa
Human OPRM1-3030H Recombinant Human OPRM1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human OPRM1-64HFL Recombinant Full Length Human OPRM1 Protein, C-Flag-tagged Mammalian cells Flag
Human OPRM1-301427H Recombinant Human OPRM1 protein, GST-tagged E.coli GST Phe352-Pro400
Human OPRM1-1583H-B Recombinant Human OPRM1 Protein Pre-coupled Magnetic Beads HEK293
Human OPRM1-301348H Recombinant Human OPRM1 protein, GST-tagged E.coli GST Met1-Ile68
Human OPRM1-391H Recombinant Human OPRM1 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-400aa
Human OPRM1-1583H Recombinant Human OPRM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse OPRM1-12176M Recombinant Mouse OPRM1 Protein Mammalian Cell His
Mouse OPRM1-6403M-B Recombinant Mouse OPRM1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Oprm1-4596M Recombinant Mouse Oprm1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse OPRM1-6403M Recombinant Mouse OPRM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat OPRM1-4196R Recombinant Rat OPRM1 Protein Mammalian Cell His
Rat OPRM1-3858R-B Recombinant Rat OPRM1 Protein Pre-coupled Magnetic Beads HEK293
Rat OPRM1-3858R Recombinant Rat OPRM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL20841BF Recombinant Full Length Bovine Mu-Type Opioid Receptor(Oprm1) Protein, His-Tagged E.coli expression system His Full Length (1-401)
Cavia porcellus (Guinea pig) RFL1146CF Recombinant Full Length Guinea Pig Mu-Type Opioid Receptor(Oprm1) Protein, His-Tagged E.coli expression system His Full Length (1-98)
Cynomolgus Monkey OPRM1-767C Recombinant Cynomolgus OPRM1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey OPRM1-511C-B Recombinant Cynomolgus Monkey OPRM1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey OPRM1-511C Recombinant Cynomolgus Monkey OPRM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL32765HF Recombinant Full Length Human Mu-Type Opioid Receptor(Oprm1) Protein, His-Tagged E.coli expression system His Full Length (1-400aa)
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RFL24258MF Recombinant Full Length Macaca Fascicularis Mu-Type Opioid Receptor(Oprm1) Protein, His-Tagged E.coli expression system His Full Length (1-400)
Macaca mulatta (Rhesus macaque) RFL7694MF Recombinant Full Length Macaca Mulatta Mu-Type Opioid Receptor(Oprm1) Protein, His-Tagged E.coli expression system His Full Length (1-400)
Mus musculus (Mouse) RFL17471MF Recombinant Full Length Mouse Mu-Type Opioid Receptor(Oprm1) Protein, His-Tagged E.coli expression system His Full Length (1-398)
Pan troglodytes (Chimpanzee) RFL11084PF Recombinant Full Length Pan Troglodytes Mu-Type Opioid Receptor(Oprm1) Protein, His-Tagged E.coli expression system His Full Length (1-401)
Rattus norvegicus (Rat) RFL5823RF Recombinant Full Length Rat Mu-Type Opioid Receptor(Oprm1) Protein, His-Tagged E.coli expression system His Full Length (1-398)
Rhesus Macaque OPRM1-3170R Recombinant Rhesus monkey OPRM1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque OPRM1-2988R Recombinant Rhesus Macaque OPRM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque OPRM1-2988R-B Recombinant Rhesus Macaque OPRM1 Protein Pre-coupled Magnetic Beads HEK293
Saimiri boliviensis boliviensis (Bolivian squirrel monkey) RFL28592SF Recombinant Full Length Saimiri Boliviensis Boliviensis Mu-Type Opioid Receptor(Oprm1) Protein, His-Tagged E.coli expression system His Full Length (1-400)
Sus scrofa (Pig) RFL6107SF Recombinant Full Length Pig Mu-Type Opioid Receptor(Oprm1) Protein, His-Tagged E.coli expression system His Full Length (1-401)
Zebrafish OPRM1-9229Z Recombinant Zebrafish OPRM1 Mammalian Cell His
Kit-0885 Maxi Protein Expression Kit N/A
Kit-0886 Protein Synthesis Kit N/A
Kit-1078 Oxalate Oxidase Activity Assay Kit (Fluorometric) N/A
Kit-1010 Cell Migration/Chemotaxis Assay Kit (24-well, 5 μm) N/A
Kit-1009 Cell Migration/Chemotaxis Assay Kit (24-well, 8 μm) N/A
Kit-1461 OPRM1 U2OS β-Arrestin-1 GPCR Assay Kit N/A
Kit-1458 cAMP OPRM1 CHO-K1 GPCR Assay Kit N/A
Kit-1462 OPRM1 Total GPCR Internalization Assay Kit N/A
Kit-1459 OPRM1 CHO K1 β-Arrestin GPCR Assay Kit N/A
Kit-1460 OPRM1 U2OS β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • OPRM1 Related Research Area

OPRM1 involved in several pathways and played different roles in them. We selected most pathways OPRM1 participated on our site, such as Neuroactive ligand-receptor interaction, Estrogen signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with OPRM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionTAAR8B;HCRTR1;GRIN2C;GRID2;S1PR4;PTGER4;CNR2;IL12;GHR
Estrogen signaling pathwayPRKACA;GNAI1;PRKCD;PRKACG;KRAS;FKBP4;MAP2K2;NRAS;GABBR2

OPRM1 has several biochemical functions, for example, G-protein alpha-subunit binding, G-protein beta-subunit binding, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OPRM1 itself. We selected most functions OPRM1 had, and list some proteins which have the same functions with OPRM1. You can find most of the proteins on our site.

Function Related Protein
G-protein alpha-subunit bindingF2R;NUCB1;CRHR1;RGS14;PPP5C;LPAR1;RIC8;AGTR1A;HTR2A
G-protein beta-subunit bindingCCT5;RGS9;GNG13;F2R;OPRM1;RGS7;F2RL1;GNG2;RASD2
G-protein coupled receptor activityGPR31;GPR21;ADRB2A;OR10W1;ADORA2AA;OR51B5;OLFR1013;OPN3;PTGER4A
beta-endorphin receptor activity
neuropeptide bindingGPR149;ADCYAP1R1;NPBWR1;MRGPRB1;NPBWR2;OPRD1B;OPRD1A;OPRD1;MC3R
protein bindingGP6;TRIM17;DIS3L2;MARCH2;PNPT1;SOX15;NR1H3;UBA52;SNRNP25
voltage-gated calcium channel activityNCS1;CACNG7;OPRM1;CACNG7A;CACNA1DA;CACNG6;CACNA1BA;CACNG3;GAS6

OPRM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OPRM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OPRM1.

WLS; RANBP9; FLNA

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