PROKR2
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Official Full Name
prokineticin receptor 2
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Overview
Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor for prokineticins. The encoded protein is similar in sequence to GPR73, another G protein-coupled receptor for prokineticins. -
Synonyms
PROKR2; prokineticin receptor 2; G protein coupled receptor 73 like 1 , GPR73L1, KAL3, Kallmann syndrome 3 (autosomal dominant); dJ680N4.3; GPR73b; GPRg2; PKR2; PK-R2; G protein-coupled receptor 73-like 1; KAL3; GPR73L1;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Bos taurus (Bovine)
- Chicken
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli expression system
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- PROKR2 Related Articles
- PROKR2 Related Research Area
PROKR2 involved in several pathways and played different roles in them. We selected most pathways PROKR2 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (q) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with PROKR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | CXCL13;LPAR2A;GPR132B;PROKR1;DRD5;GPR37B;XK;GPR17;PROKR1A |
| G alpha (q) signalling events | EDN3;ABHD6B;OPN4A;TAC2;NMU;DGKB;RGS19;OXTRL;CHRM1 |
| GPCR downstream signaling | NTS;SSTR1;GCGA;CCL19A.2;ARHGEF17;SST;ARHGEF18A;RGS19;APPB |
| GPCR ligand binding | CCL27;ZFPM2B;GPBAR1;HEBP1;OPN4;EDN3;ADRA2B;EMR1;PROKR1 |
| GPCRs, Other | VMN1R46;CELSR1;EMR2;GPR84;ADORA3;GPR18;V1RA8;VMN1R50;GPR176 |
| Gastrin-CREB signalling pathway via PKC and MAPK | GRP;LPAR2A;OPN4B;DGKQ;GCGB;DGKA;OXTRL;KISS1;NMU |
| Peptide ligand-binding receptors | RLN3;NPS;KISS1;PNOC;CXCR7B;SSTR5;CCL35.2;PPY;CCL35.1 |
| Signal Transduction | ARHGAP17;NTS;CRABP2A;IFT88;ARHGAP12B;NET1;CDC42EP1B;ABHD12;EVC |
PROKR2 has several biochemical functions, for example, G-protein coupled receptor activity, neuropeptide Y receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PROKR2 itself. We selected most functions PROKR2 had, and list some proteins which have the same functions with PROKR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | LPAR5;GPRC5BB;PROKR1A;GPR132B;TAAR13B;FPR2;TAAR12J;VMN1R40;GPR20 |
| neuropeptide Y receptor activity | NPY2R;PRLHR2B;NPY8BR;QRFPR;PROKR2;PROKR1;NPY8AR;NPY1R;PRLHR2A |
PROKR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PROKR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PROKR2.
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