PSMD9
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Official Full Name
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
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Overview
p27 is a cyclin-dependent kinase inhibitor which regulates progression from G1 to S phase by binding and inhibiting cyclin-dependent kinases. Low p27 expression has been associated with unfavorable prognosis in renal cell carcinoma, colon carcinoma, small -
Synonyms
PSMD9; proteasome (prosome, macropain) 26S subunit, non-ATPase, 9; 26S proteasome non-ATPase regulatory subunit 9; p27; Rpn4; homolog of rat Bridge 1; 26S proteasome regulatory subunit p27; proteasome 26S non-ATPase regulatory subunit 9; MGC8644;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
PSMD9 involved in several pathways and played different roles in them. We selected most pathways PSMD9 participated on our site, such as APC/C-mediated degradation of cell cycle proteins, APC/C:Cdc20 mediated degradation of Securin, APC/C:Cdc20 mediated degradation of mitotic proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| APC/C-mediated degradation of cell cycle proteins | NEK2;CDK2;PSMD5;PSMD14;ANAPC10;PSME3;PSMD9;AURKB;PSMD10 |
| APC/C:Cdc20 mediated degradation of Securin | PSMD14;PSME3;PSMD5;ANAPC10;PSMD9;PSMD10;PSMA8;UBE2C |
| APC/C:Cdc20 mediated degradation of mitotic proteins | UBE2C;PSMD5;PSMD9;PSMA8;PSME3;PSMD10;PSMD14;NEK2;ANAPC10 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | PSMA8;ANAPC10;PSMD14;PSMD9;UBE2C;PSMD5;PSMD10;AURKB;PSME3 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | UBE2C;NEK2;PSMA8;PSMD5;PSMD9;PSMD10;PSME3;ANAPC10;PSMD14 |
| ARMS-mediated activation | DUSP2;RASGEF1A;PEBP1;FGF18B;NETO2;NRG2A;NRG3;KBTBD7;FRS2B |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | PSMD10;PSMA8;HNRNPD;PSMD5;PSMD9;EIF4G1;PSMD14;PSME3 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | ANAPC10;PSMD10;PSMD5;PSMD9;PSMD14;UBE2C;NEK2;PSMA8;PSME3 |
PSMD9 has several biochemical functions, for example, bHLH transcription factor binding, protein binding, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD9 itself. We selected most functions PSMD9 had, and list some proteins which have the same functions with PSMD9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| bHLH transcription factor binding | TCF21;ISL1;ASCL1;TCF3B;USF1;SIRT1;TCF3A;PSMD9;SMAD3 |
| protein binding | C19orf40;SEC22A;PARP4;CNOT8;SELP;SYAP1;PARD6A;DCP1B;AAAS |
| transcription coactivator activity | MAGED1;ESR2;PSMC3;MYSM1;MYOCD;SUPT3H;TADA1;ZSCAN1;GATA3 |
PSMD9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD9 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD9.
PSMC6; PSMC3; TRIM39
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