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Official Full Name
RE1-silencing transcription factor
This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of;the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element;called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor;cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively;spliced transcript variants have been described.
REST; RE1-silencing transcription factor; NRSF; XBR; Neural Restrictive Silencer Factor; Neural-restrictive silencer factor; Neuron Restrictive Silencer Factor; RE1 silencing transcription factor; Repressor binding to the X2 box; REST protein; REST_HUMAN; X2 box repressor