SerpinB1
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Official Full Name
serpin peptidase inhibitor, clade B (ovalbumin), member 1
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Overview
Leukocyte elastase inhibitor (LEI) also known as serpin B1 is a protein that in humans is encoded by the SERPINB1 gene. -
Synonyms
SERPINB1; serpin peptidase inhibitor, clade B (ovalbumin), member 1; ELANH2, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; leukocyte elastase inhibitor; anti elastase; EI; PI2; ELANH2; ILEU_HUMAN; LEI; M/NEI; MNEI; Monocyte/neutrophil elastase inhibitor; Peptidase inhibitor 2; Pi-2; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 1; Serpin B1; Serpin peptidase inhibitor clade B (ovalbumin) member 1; anti-elastase; protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Pig
- Rhesus Macaque
- Zebrafish
- Baculovirus-Insect cells
- E. coli
- E.coli
- HEK293
- In Vitro Cell Free System
- Insect Cell
- Insect Cells
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- Flag
- His (Fc)
- Avi
- Myc
- SUMO
- Myc|DDK
- N/A
- N
- Tag Free
- Involved Pathway
- Protein Function
- Interacting Protein
- SerpinB1 Related Articles
- SerpinB1 Related Research Area
SerpinB1 involved in several pathways and played different roles in them. We selected most pathways SerpinB1 participated on our site, such as Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SerpinB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Amoebiasis | SERPINB1B;SERPINB3;CD1D;PIK3CA;COL27A1;LAMA2;LAMA4;ITGB2L;PRKCB |
SerpinB1 has several biochemical functions, for example, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SerpinB1 itself. We selected most functions SerpinB1 had, and list some proteins which have the same functions with SerpinB1. You can find most of the proteins on our site.
Function | Related Protein |
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serine-type endopeptidase inhibitor activity | SPINK10;GOPC;SPINK2;SPINK13;HRG;COL28A1;APLP2;SERPINB1B;SERPINB12 |
SerpinB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SerpinB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SerpinB1.
icmF2; q9k5j5_bacan; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate
- Q&As
- Reviews
Q&As (7)
Ask a questionIt inhibits neutrophil elastase and cathepsin G, balancing proteolysis.
Its expression and activity are regulated by various signaling pathways and transcription factors.
Potential therapeutic applications could involve modulating SERPINB1 to mitigate damage in inflammatory and infectious diseases.
It helps control inflammation by modulating protease activity in immune responses.
SERPINB1 functions as a serine protease inhibitor, regulating protease activity.
SERPINB1 protects tissues from damage during inflammation and infection.
SERPINB1 is predominantly expressed in neutrophils and some other immune cells.
Customer Reviews (3)
Write a reviewQuick, efficient, reliable service.
Worked great, highly pure.
Excellent for molecular experiments.
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