Creative BioMart to Present at IMMUNOLOGY2024™|May 3-7, 2024|Booth #512 Learn More

SLC24A4

Official Full Name

solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
Overview

This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.
Synonyms

SLC24A4; solute carrier family 24 (sodium/potassium/calcium exchanger), member 4; sodium/potassium/calcium exchanger 4; NCKX4; Na(+)/K(+)/Ca(2+)-exchange protein 4; NCKX4_HUMAN; Solute carrier family 24 member 4; SHEP6; SLC24A2;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SLC24A4-1296H	Recombinant Human SLC24A4 Protein (A2-D622), 8×His-MBP, Flag tagged	Insect Cell	8His-MBP,Flag	A2-D622	Inquiry
Mouse	SLC24A4-15291M	Recombinant Mouse SLC24A4 Protein	Mammalian Cell	His		Inquiry
Mouse	SLC24A4-8268M	Recombinant Mouse SLC24A4 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	SLC24A4-8268M-B	Recombinant Mouse SLC24A4 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
SLC24A4 Related Articles

SLC24A4 involved in several pathways and played different roles in them. We selected most pathways SLC24A4 participated on our site, such as Olfactory transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC24A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Olfactory transduction	SLC8A2;GNB1;OLFR488;OR1L1;OLFR491;OR4D6;OLFR497;OR12D2;OR2J3

SLC24A4 has several biochemical functions, for example, antiporter activity, calcium channel activity, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC24A4 itself. We selected most functions SLC24A4 had, and list some proteins which have the same functions with SLC24A4. You can find most of the proteins on our site.

Function	Related Protein
antiporter activity	SLC7A3A;SLC7A1;SLC9A9;CLCN5;SLC26A3.1;SLC4A8;SLC47A1;SLC9A5;SLC7A4
calcium channel activity	TRPC6A;CACNA1SB;CHRNA9;TRPC4A;TRPV2;GRIN3A;PKD1;GRIN2A;TRPN1
calcium ion binding	CALN1;MMP13A;EFCAB9;MYL12.2;PCDH8;EFHC2;PCDH2AB9;MATN2;LPCAT2
calcium, potassium:sodium antiporter activity	SLC24A2;SLC24A1;SLC24A5;SLC24A4;SLC24A4A
calcium:sodium antiporter activity	SLC8A2A;SLC24A4;SLC8A2;SLC8A1B;SLC8A1;SLC8A4B;SLC24A6;SLC8A4A;SLC8A1A
potassium ion binding	PKM2;SLC24A4A;PKMA;PKMB;ATP1A1;SLC24A5;HDAC4;SLC24A2;KCNA4
sodium ion binding	SLC24A2;SCN9A;SLC24A1;SLC24A5;CAPN3;SLC34A2;ATP1A1;SLC24A4A;PDXK
symporter activity	SLC12A3;SLC1A2B;SLC20A1B;SLC25A22;SLC6A16B;SLC1A3A;SLC25A18;SLC6A6B;SLC17A6B

SLC24A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC24A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC24A4.

Herzog, CR; Reid, BM; et al. Hypomaturation amelogenesis imperfecta caused by a novel SLC24A4 mutation. ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY 119:E77-E81(2015).

Yu, L; Chibnik, LB; et al. Association of Brain DNA Methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 With Pathological Diagnosis of Alzheimer Disease. JAMA NEUROLOGY 72:15-24(2015).