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SPC24

  • Official Full Name

    SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)

  • Synonyms

    SPBC24;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SPC24-1528HCL Recombinant Human SPC24 293 Cell Lysate HEK293 N/A
Human SPC24-3234H Recombinant Human SPC24 protein, His-tagged E.coli His 1-197 aa
Human SPC24-5620H Recombinant Human SPC24 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse SPC24-15850M Recombinant Mouse SPC24 Protein Mammalian Cell His
Mouse SPC24-8629M Recombinant Mouse SPC24 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SPC24-8629M-B Recombinant Mouse SPC24 Protein Pre-coupled Magnetic Beads HEK293
Mouse Spc24-6084M Recombinant Mouse Spc24 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque SPC24-4428R Recombinant Rhesus monkey SPC24 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SPC24-4244R Recombinant Rhesus Macaque SPC24 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SPC24-4244R-B Recombinant Rhesus Macaque SPC24 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SPC24-3038Z Recombinant Zebrafish SPC24 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SPC24 Related Articles

SPC24 involved in several pathways and played different roles in them. We selected most pathways SPC24 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPC24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell CycleDNA2;TFDP2;MAD2L1;CDKN2A;HTATIP;NUP35;PRKDC;E2F3;DSN1
Cell Cycle, MitoticMAU2;CEP57;NEK9;LIN37;TUBG1;DCTN1;SKA2;TUBB4A;PLK4
M PhaseCNEP1R1;ZWILCH;CTDNEP1;NSL1;APITD1;STAG2;NDC80;PANE1;ARPP19B
Mitotic AnaphaseCENPL;ANKLE2;CDCA8;SPDL1;CENPO;CENPP;CENPQ;MLF1IP;ERCC6L
Mitotic Metaphase and AnaphaseSPDL1;NSL1;CENPO;CENPE;NDEL1A;CENPL;ANKLE2;NUDC;ITGB3BP
Mitotic PrometaphaseCENPH;PMF1;NSL1;CCDC99;SKA2;NCAPD2;CENPN;CENPK;CLIP1
PLK1 signaling eventsTPT1;SPC24;TPX2;ERCC6L;TCTN2;ECT2;BORA;NDC80;PLK1S1
RHO GTPase EffectorsEVL;AHCTF1;SPC25;KNTC1;NOXO1A;WASF3;LIN7B;WIPF2;MIS12

SPC24 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPC24 itself. We selected most functions SPC24 had, and list some proteins which have the same functions with SPC24. You can find most of the proteins on our site.

Function Related Protein
protein bindingFUT11;RNF40;LOX;VAPB;TTYH2;MALT1;HSPB8;RHOB;KLF6

SPC24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPC24 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPC24.

NDC80; SPC25; ZWINT; MIS12

Petrovic, A; Mosalaganti, S; et al. Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization. MOLECULAR CELL 53:591-605(2014).
Malvezzi, F; Litos, G; et al. A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors. EMBO JOURNAL 32:409-423(2013).
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