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TERF2IP

Official Full Name

telomeric repeat binding factor 2, interacting protein
Overview

Telomeric repeat-binding factor 2-interacting protein (TERF2IP, also known as RAP1) is a component of the Shelterin Complex, a multi-protein complex that binds and organizes telomeres into T-loop structures to prevent them from being recognized by the cel
Synonyms

TERF2IP; telomeric repeat binding factor 2, interacting protein; telomeric repeat-binding factor 2-interacting protein 1; RAP1; hRap1; RAP1 homolog; TRF2-interacting telomeric protein 1; TERF2-interacting telomeric protein 1; repressor/activator protein 1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TERF2IP-3181H	Recombinant Human TERF2IP, His-tagged	E.coli	His	0-268aa	$319 / 25ug
Human	TERF2IP-30H	Recombinant Human TERF2IP protein, GST-tagged	Wheat Germ	GST	1 a.a. - 399 a.a.	Inquiry
Human	TERF2IP-1145HCL	Recombinant Human TERF2IP 293 Cell Lysate	HEK293	N/A		Inquiry
Human	TERF2IP-681HF	Recombinant Full Length Human TERF2IP Protein, GST-tagged	In Vitro Cell Free System	GST	399 amino acids	Inquiry
Mouse	TERF2IP-16645M	Recombinant Mouse TERF2IP Protein	Mammalian Cell	His		Inquiry
Mouse	TERF2IP-9131M	Recombinant Mouse TERF2IP Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	TERF2IP-9131M-B	Recombinant Mouse TERF2IP Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	TERF2IP-6013R	Recombinant Rat TERF2IP Protein	Mammalian Cell	His		Inquiry
Rat	TERF2IP-5672R-B	Recombinant Rat TERF2IP Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	TERF2IP-5672R	Recombinant Rat TERF2IP Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	TERF2IP-7954Z	Recombinant Zebrafish TERF2IP	Mammalian Cell	His		Inquiry
Chicken	TERF2IP-6038C	Recombinant Chicken TERF2IP	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

TERF2IP involved in several pathways and played different roles in them. We selected most pathways TERF2IP participated on our site, such as Cell Cycle, Cellular Senescence, Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with TERF2IP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell Cycle	CCND3;CDK11B;ORC1;RNF168;TERF1;GORASP1;ANAPC4;ORC3;TBC1D8
Cellular Senescence	KDM6B;AGO1;CABIN1;HIST1H1A;HIST1H1D;POT1A;CBX8A;CBX8B;MINK1
Cellular responses to stress	TINF2;EEF1A1;WDR45L;DYNLL2B;HIST3H2BB;AMBRA1B;AMBRA1A;KDM6B;HMGA1B
Chromosome Maintenance	ITGB3BP;CENPW;POT1;CENPO;TERF2IP;NPM1;CENPC1;MIS18A;CENPK
DNA Damage/Telomere Stress Induced Senescence	HMGA1;HIRA;HTATIP;ACD;EP400;TERF2IP;CABIN1;HIST1H1E;POT1A
Hypothetical Network for Drug Addiction	ACTA1B;TERF2IP;ZHX2;ACTA1;CX28.8;NISCH;GJB7
Meiosis	TEX12;FKBP6;MND1;TERF1;PSMC3IP;MSH4;STAG2;DMC1;TEX15
Meiotic synapsis	FKBP6;ACD;TEX12;POT1A;SYNE1;SYCP2;DIDO1;SYCP1;SYCE2

TERF2IP has several biochemical functions, for example, protein binding, NOT telomeric DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TERF2IP itself. We selected most functions TERF2IP had, and list some proteins which have the same functions with TERF2IP. You can find most of the proteins on our site.

Function	Related Protein
protein binding	NDUFS1;GAPDHS;FSCN1;BAG4;LSM7;ATP6V1D;KIT;THRB;TATDN1
NOT telomeric DNA binding

TERF2IP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TERF2IP here. Most of them are supplied by our site. Hope this information will be useful for your research of TERF2IP.

TERF2; XRCC6; ACD; SLX4