TESK1
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Official Full Name
testis-specific kinase 1
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Overview
Testis-specific kinase 1 (TESK1) is a LIMK-related protein kinase originally identified to be expressed highly in testes and subsequently shown to be expressed in a wide variety of tissues and cell types (1-4). TESK1 phosphorylates the actin severing prot -
Synonyms
TESK1; testis-specific kinase 1; dual specificity testis-specific protein kinase 1; testis specific kinase 1; testicular protein kinase 1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- Insect (sf21)
- Mammalian Cell
- Sf9 Insect Cell
- GST
- His
- His (Fc)
- Avi
- His|T7
- Involved Pathway
- Protein Function
- Interacting Protein
TESK1 involved in several pathways and played different roles in them. We selected most pathways TESK1 participated on our site, such as Cell junction organization, Cell-Cell communication, Cell-extracellular matrix interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with TESK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell junction organization | CDH7;CDH6;COL17A1;PVRL2L;CLDN4;PARVB;CDH24;JUPA;DST |
| Cell-Cell communication | KIRRELB;RSU1;CLDN7;CDH2;CDH12;CD151;CADM2;KIRREL;NPHS1 |
| Cell-extracellular matrix interactions | ITGB1B.1;LIMS1;FERMT2;FBLIM1;PARVB;TESK1;RSU1 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | LIMS1;RSU1;PARVB;TESK1 |
TESK1 has several biochemical functions, for example, ATP binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TESK1 itself. We selected most functions TESK1 had, and list some proteins which have the same functions with TESK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | RNASEL;HLCS;RET;GRK1;P2RX4;CLK4;FAM20B;BAT1;CDKL3 |
| metal ion binding | ZNF688;ZNF43;ADIPOR2;DNAJA2;BHLHE22;BGLAP2;ZFP523;TREX1;GALNTL2 |
| protein binding | CD200R2;APC;F2;CALM1;NOL11;VPS4A;TIMM50;LRRK1;MAP4K5 |
| protein serine/threonine kinase activity | PLK2;DAPK2;GRK7B;SIK2A;VRK1;EIF2AK4;PIK3CA;MAP2K7;CSNK1G2B |
| protein serine/threonine/tyrosine kinase activity | TNK2;RPS6KB1;PRKAA2;PRKACA;CLK4;DYRK4;ACVR2B;DYRK1A;TESK2 |
| protein tyrosine kinase activity | ROS1;FGFR1;ABL1;CLK4;FGR;EPHA4A;ZNF143B;EPHB2;JAK2 |
TESK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TESK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TESK1.
YWHAB; SPRY4; HSP90AB1; ARAF; PFKL; ABCB4; YY1
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