TMSB4X
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Official Full Name
thymosin beta 4, X-linked
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Overview
Thymosin beta-4 is a protein that in humans is encoded by the TMSB4X gene. The protein consists (in humans) of 44 amino acids (msdkpdmaei ekfdksklkk tetqeknplp sketieqekq ages) molWt 4921. This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. Thymosin beta-4 was shown to be essential for all aspects of coronary vessel development in mice; it stimulates significant outgrowth from quiescent adult epicardial explants, restoring pluripotency and triggering differentiation of fibroblasts, smooth muscle cells, and endothelial cells -
Synonyms
TMSB4X; FX; PTMB4; TB4X; TMSB4; thymosin beta 4, X-linked; OTTHUMP00000022927; prothymosin beta-4; thymosin, beta 4, X chromosome; thymosin beta-4; T beta-4; THYB4; Thymosin Beat 4;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Horse
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293F
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- SUMO
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- TMSB4X Related Articles
- TMSB4X Related Research Area
TMSB4X involved in several pathways and played different roles in them. We selected most pathways TMSB4X participated on our site, such as Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with TMSB4X were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Regulation of actin cytoskeleton | MYL9B;FGF1A;VAV3B;DIAP1;Itga10&Itgb1;PPP1CAA;Itgam&Itgb2;GIT1;ITGA3 |
TMSB4X has several biochemical functions, for example, actin monomer binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMSB4X itself. We selected most functions TMSB4X had, and list some proteins which have the same functions with TMSB4X. You can find most of the proteins on our site.
Function | Related Protein |
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actin monomer binding | CORO1A;LIMA1;TMSB10;MYL4;TMSB4Y;COBL;PRKCE;COBLL1;MTSS1 |
poly(A) RNA binding | AGO1;HIST1H1C;DHX16;PTBP1;SFPQ;DIDO1;MRPS23;ARHGEF1;LARP2 |
protein binding | TMEM115;RBL1;CCDC170;FAAH;CSNK2B;MRPL12;PTPRE;KEAP1;KAL1 |
TMSB4X has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMSB4X here. Most of them are supplied by our site. Hope this information will be useful for your research of TMSB4X.
MLH1; SCHIP1; TK1; TP53; ANXA7
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