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TPD52L2

Official Full Name

tumor protein D52-like 2
Overview

This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12.
Synonyms

TPD52L2; tumor protein D52-like 2; tumor protein D54; D54; hD54; TPD54; 2810411G23Rik; AU016537; C86069; DKFZp686A1765; MGC73020; RP23 33L3.2; TPD54_HUMAN; tumor protein D52 like 2; OTTHUMP00000031612; OTTHUMP00000031613; OTTHUMP00000031614; OTTHUMP00000031615; OTTHUMP00000031616; OTTHUMP00000031617; HCCR-binding protein 2;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	TPD52L2-1814HCL	Recombinant Human TPD52L2 cell lysate		N/A	Inquiry
Human	TPD52L2-2437H	Recombinant Human TPD52L2 Protein, MYC/DDK-tagged	HEK293	Myc/DDK	Inquiry
Mouse	Tpd52l2-6593M	Recombinant Mouse Tpd52l2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Rat	TPD52L2-6237R	Recombinant Rat TPD52L2 Protein	Mammalian Cell	His	Inquiry
Rat	TPD52L2-5894R	Recombinant Rat TPD52L2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	TPD52L2-5894R-B	Recombinant Rat TPD52L2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Chicken	TPD52L2-2552C	Recombinant Chicken TPD52L2	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
TPD52L2 Related Articles

TPD52L2 involved in several pathways and played different roles in them. We selected most pathways TPD52L2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TPD52L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TPD52L2 has several biochemical functions, for example, poly(A) RNA binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TPD52L2 itself. We selected most functions TPD52L2 had, and list some proteins which have the same functions with TPD52L2. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	NXF3;RSL24D1;U2AF1;NOL10;DDX17;UBC;FIP1L1;RBM12;NOL6
protein binding	FAM127A;MICA;FAM46A;NTF4;PPP1R15B;CD24;LRRK1;USP6;TGFB1
protein heterodimerization activity	SMC1A;HEXB;TYRP1;CEBPB;HGF;UGT1A4;PEF1;SPTAN1;BMP7A
protein homodimerization activity	OXCT1;PON3;ABCB10;PDE2A;APOC2;KCNE2;PVRL3;BCL2L2;IZUMO1

TPD52L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TPD52L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TPD52L2.

IKBKE; APP; ADORA2B; mtaD; q8d1p4_yerpe; 1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate

He, YC; Chen, FS; et al. Knockdown of tumor protein D52-like 2 induces cell growth inhibition and apoptosis in oral squamous cell carcinoma. CELL BIOLOGY INTERNATIONAL 39:264-271(2015).

Yang, M; Wang, XY; et al. Tumor Protein D52-Like 2 Contributes to Proliferation of Breast Cancer Cells. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 30:1-7(2015).