TREML2
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Official Full Name
triggering receptor expressed on myeloid cells-like 2
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Overview
TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1;(MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003;(PubMed 12645956)). -
Synonyms
TREML2; triggering receptor expressed on myeloid cells-like 2; trem-like transcript 2 protein; TLT-2; triggering receptor expressed on myeloid cells-like protein 2; triggering receptor expressed on myeloid cells-like 2a dominant; Tlt2; Gm750; AW049306;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- HEK293
- Human Cell
- Mammalian Cell
- Mammalian cells
- Fc
- Fc Chimera
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | TREML2-521H | Active Recombinant Human TREML2, Fc Chimera | Mammalian cells | Fc Chimera |
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| Human | TREML2-427H | Recombinant Human TREML2 Protein, Fc-tagged | HEK293 | Fc |
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| Human | TREML2-3227H | Recombinant Human TREML2 protein, His-tagged | HEK293 | His | Met1-Ser268 | |
| Human | TREML2-2237HCL | Recombinant Human TREML2 cell lysate | Human Cell | N/A |
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| Human | TREML2-212H-B | Recombinant Human TREML2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Human | TREML2-212H | Recombinant Human TREML2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | TREML2-17323M | Recombinant Mouse TREML2 Protein | Mammalian Cell | His |
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| Mouse | TREML2-9581M | Recombinant Mouse TREML2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | TREML2-9581M-B | Recombinant Mouse TREML2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Chicken | TREML2-3625C | Recombinant Chicken TREML2 | Mammalian Cell | His |
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| Chicken | TREML2-3627C | Recombinant Chicken TREML2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- TREML2 Related Research Area
TREML2 involved in several pathways and played different roles in them. We selected most pathways TREML2 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with TREML2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | KIF26A;DNM1;CSK;OSCAR;DYNC1H1;KIF4A;RNF14;CREB1;FAM49BA |
| Immune System | ASB2;GHRB;HLA-DQB2;CTSH;TRIM41;CD180;ATP6V1G3;SOCS3A;TAX1BP1 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | KLRB1F;SIGLEC8;SIGLEC6;TREML2;SIGLEC7;KLRB1B;LILRB3;CLEC2H;GM11711 |
TREML2 has several biochemical functions, for example, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TREML2 itself. We selected most functions TREML2 had, and list some proteins which have the same functions with TREML2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | LRRC4C;MET;SYT7;RACGAP1;SMNDC1;TSHZ3;BCKDHB;NME2;PSAP |
| receptor activity | LRP1;CD226;NPR2;MRC1;KLRG1;CLEC4E;LILRB4;CADM1;ANPEP |
TREML2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TREML2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TREML2.
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