UMOD
-
Official Full Name
uromodulin
-
Overview
The Tamm-Horsfall glycoprotein (THP) also known as uromodulin is a glycoprotein that in humans is encoded by the UMOD gene.[1][2] Uromodulin is the most abundant protein in normal urine. -
Synonyms
UMOD; uromodulin; THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Native Proteins
- Dog
- Human
- Mouse
- Pig
- Rat
- E.coli
- HEK293
- HEK293T
- Human Urine
- Mammalian Cell
- Mammalian cells
- Porcine Urine
- Yeast
- Flag
- GST
- His
- His (Fc)
- Avi
- His|GST
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- UMOD Related Research Area
UMOD involved in several pathways and played different roles in them. We selected most pathways UMOD participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with UMOD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|
UMOD has several biochemical functions, for example, IgG binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UMOD itself. We selected most functions UMOD had, and list some proteins which have the same functions with UMOD. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
IgG binding | FCGR1;PIP;FCGR3A;UMOD;FCGR2A;FCGR2B;FCER1G;FCGR3B;FCGR2C |
calcium ion binding | DSG1C;S100A11;HSPA5;PVALB8;THBS3;KCNIP3A;ANXA8;S100A1;CAPSLB |
UMOD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UMOD here. Most of them are supplied by our site. Hope this information will be useful for your research of UMOD.
ycgG; q81t34_bacan
- Q&As
- Reviews
Q&As (7)
Ask a questionDeficiency or mutations in UMOD can lead to kidney disorders like tubulointerstitial nephritis, affecting kidney structure and function.
UMOD plays a crucial role in regulating salt and water reabsorption in the kidneys, affecting fluid balance.
UMOD is key in maintaining kidney and urinary tract health, influencing urine concentration and kidney function.
UMOD impacts the development and progression of CKD, influencing kidney filtration and health.
UMOD contributes to the immune defense in the urinary system, protecting against infections and inflammation.
Changes in UMOD function can impact blood pressure and cardiovascular health, due to its role in kidney function and fluid balance.
UMOD affects the formation of kidney stones, potentially influencing their development and composition.
Customer Reviews (3)
Write a reviewEfficient protein purification, crucial for our research. Highly recommended.
Accurate protein structural analysis, a critical component of our investigations.
Exceptional protein expression optimization support, greatly enhances our research.
Ask a Question for All UMOD Products
Required fields are marked with *
My Review for All UMOD Products
Required fields are marked with *