VCX3A

Official Full Name

variable charge, X-linked 3A

Background

This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit.

Synonyms

VCX3A; variable charge, X-linked 3A; variable charge, X linked 3 , VCX3; variable charge X-linked protein 3; VCX 8r; VCX 8R; VCX A; MGC118976; MGC125730; MGC125796; Variable charge protein on X with eight repeats; Variable charge X linked 3A; Variable charge X linked protein 3; Variably charged protein X A; Variably charged X A; VCX 3; VCX 3A; VCX 8R; VCX A; VCX3; VCX8R; VCXA; OTTHUMP00000022866; variably charged X-A; variably charged protein X-A; variable charge protein on X with eight repeats; VCX3; VCXA; VCX-A; VCX8R; VCX-8r;