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Official Full Name
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to;phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this;protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein,;suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5 UTR but that;encode the same protein have been identified for this gene.
YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; 14-3-3 protein zeta/delta; SEZ-2; KCIP-1; protein kinase C inhibitor protein 1; AI596267; AL022924; AU020854; 14-3-3zeta; 1110013I11Rik