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ABP1

Official Full Name

amiloride binding protein 1 (amine oxidase (copper-containing))
Overview

This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
Synonyms

ABP1; amiloride binding protein 1 (amine oxidase (copper-containing)); amiloride-sensitive amine oxidase [copper-containing]; AOC1; DAO; ABP; ABP1_HUMAN; Amiloride binding protein 1 (amine oxidase (copper containing)); Amiloride binding protein 1; Amiloride binding protein; Amiloride sensitive amine oxidase; Amiloride-binding protein; DAO1; Diamine oxidase; Histaminase; KAO; Kidney amine oxidase; amiloride-binding protein-1; amiloride-sensitive amine oxidase;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Maize
Rat

Source

E.coli
E.Coli or Yeast
HEK293
HEK293F
In Vitro Cell Free System
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ABP1-112H	Recombinant Human ABP1 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	ABP1-9255H	Recombinant Human ABP1, GST-tagged	E.coli	GST	400-751a.a.	$319 / 25ug
Human	ABP1-3409H	Recombinant Human ABP1, His-tagged	E.Coli or Yeast	His	751	Inquiry
Human	ABP1-113H	Recombinant Human ABP1 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	ABP1-114H	Recombinant Human ABP1 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	ABP1-9123HCL	Recombinant Human ABP1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	ABP1-15H	Recombinant Human ABP1 Protein, His-tagged	HEK293F	N-His	Glu20-Val751	Inquiry
Human	ABP1-834HF	Recombinant Full Length Human ABP1 Protein, GST-tagged	In Vitro Cell Free System	GST	751 amino acids	Inquiry
Human	ABP1-16H	Recombinant Human ABP1 Protein, His-tagged	E.coli	N-His	Thr400-Val751	Inquiry
Human	ABP1-832HF	Recombinant Full Length Human ABP1 Protein, GST-tagged	In Vitro Cell Free System	GST	751 amino acids	Inquiry
Rat	Abp1-3410R	Recombinant Rat Abp1, His-tagged	E.Coli or Yeast	His	746	Inquiry
Maize	ABP1-3862M	Recombinant Maize ABP1 protein, His-tagged	E.coli	His	39-201aa	Inquiry
Maize	ABP1-1265M	Recombinant Maize ABP1 Protein (39-201 aa), His-tagged	E.coli	His	39-201 aa	Inquiry

Involved Pathway
Protein Function
Interacting Protein
ABP1 Related Articles

ABP1 involved in several pathways and played different roles in them. We selected most pathways ABP1 participated on our site, such as Arginine and proline metabolism, Histidine metabolism, Tryptophan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Arginine and proline metabolism	AGMAT;CKB;ALDH2.2;ALDH2;NOS1;ALDH9A1B;SAT1;DAO.2;GOT2A
Histidine metabolism	CNDP1;ALDH9A1;HNMT;ALDH3A2;ALDH2.2;HDC;ALDH3B1;CARNS1;MAOA
Tryptophan metabolism	TDO2;OGDHL;ANI_1_2390104;HADHAA;TDO2B;TDO2A;ALDH9A1;AANAT2;AOC1
Metabolic pathways	PLA2G12A;NAT2;EXT1B;PLB1;PGS1;HDC;COQ7;ALDH1A3;POLR3K

ABP1 has several biochemical functions, for example, calcium ion binding, copper ion binding, diamine oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABP1 itself. We selected most functions ABP1 had, and list some proteins which have the same functions with ABP1. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	PCDH2AB6;NCALD;EYS;CAPN13;PCDH15;F9A;MAN1A;DGKA;EDEM2
copper ion binding	TYRP1;P2RX4;MOXD1;HEPHL1A;SCO1;MT1;HIST2H3A;SCO2;PRNP
diamine oxidase activity
drug binding	HTR2B;RARB;SRP54A;CYP2D6;SETD6;MT2A;DAAM2;TYMS;SFRP1
heparin binding	ELANE;FBLN7;WISP1;LTBP2;F11;CCL23;APOA5;AAMP;APOE
histamine oxidase activity
methylputrescine oxidase activity
primary amine oxidase activity	AOC3;AOC2;VCAM1;MAOB;MAOA;AOC1;ABP1
propane-1,3-diamine oxidase activity
protein complex binding	RELA;PDCL;C8G;UGT1A6B;KCTD5;SIX2;PTPRF;RXRA;HSPD1
protein homodimerization activity	TBX15;YARS2;CHMP1A;S100A13;TERFA;B4GALT1;S100A5;PLDN;IZUMO1
quinone binding	AOC1;ETFDH;AOC2;CBR4;HHIP;NDUFS7;VKORC1;ABP1;SQRDL
receptor activity	CLEC4E;SLC40A1;NOTCH1A;NLGN4B;PAQR5A;GPA33;TREML2;MCC;TLR6
zinc ion binding	NR4A3;KDM4B;SETDB1;RNFT2;PRICKLE2B;MARCH6;TRIM55;SRSF7;SH3RF2

ABP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABP1.

Grandits, M; Oostenbrink, C; et al. Molecular dynamics simulations of the auxin-binding protein 1 in complex with indole-3-acetic acid and naphthalen-1-acetic acid. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 82:2744-2755(2014).

Seeley-Fallen, MK; Liu, LJ; et al. Actin-binding protein 1 links B-cell antigen receptors to negative signaling pathways. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:9881-9886(2014).