ACCN2
-
Official Full Name
amiloride-sensitive cation channel 2, neuronal
-
Overview
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown. Alternative splicing of this gene generates 2 transcript products. -
Synonyms
ACCN2; amiloride-sensitive cation channel 2, neuronal; ASIC1; BNaC2; hBNaC2; neuronal; ACCN2_HUMAN; Acid sensing ion channel 1; Acid sensing ion channel 1a protein; Acid sensing ion channel; Acid-sensing ion channel 1; AI843610; Amiloride sensitive cation channel 2 neuronal; Amiloride-sensitive cation channel 2; ASIC; ASIC1A; B530003N02Rik; Brain sodium channel 2; Cation channel amiloride sensitive neuronal 2; ACCN2 variant 3; acid-sensing ion channel 1a protein; Cation channel, amiloride-sensitive, neuronal, 2;
- Recombinant Proteins
- Antibody
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rhesus Macaque
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ACCN2-04HF | Recombinant Full Length Human ACCN2 Protein | In Vitro Cell Free System | 528 amino acids | ||
Human | ACCN2-26289TH | Recombinant Human ACCN2 | Wheat Germ | N/A | 528 amino acids | |
Rhesus Macaque | ACCN2-204R | Recombinant Rhesus monkey ACCN2 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | ACCN2-33R | Recombinant Rhesus Macaque ACCN2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | ACCN2-33R-B | Recombinant Rhesus Macaque ACCN2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Chicken | ACCN2-3416C | Recombinant Chicken ACCN2 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- ACCN2 Related Articles
ACCN2 involved in several pathways and played different roles in them. We selected most pathways ACCN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ACCN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|
ACCN2 has several biochemical functions, for example, acid-sensing ion channel activity, ion gated channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACCN2 itself. We selected most functions ACCN2 had, and list some proteins which have the same functions with ACCN2. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
acid-sensing ion channel activity | ASIC1A;ASIC1;ASIC1B;ACCN2;ASIC1C |
ion gated channel activity | ASIC1;ACCN2 |
ACCN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACCN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACCN2.
- Q&As
- Reviews
Q&As (10)
Ask a questionIt varies depending on the specific experimental application. You can seek technical support from our experts for guidance on the appropriate protein concentration for your desired assay or study.
Common applications may include biochemical assays, protein-protein interaction studies, functional studies, or as an antigen for antibody development.
Yes, we have a team of technical experts who can help.
No, but please feel free to submit any specific requirements, and our team of experts will reach out to you accordingly.
Certainly, you have the option to provide detailed information about the mutation site in the online form, and our team of scientists will customize the appropriate protein products exclusively for your needs.
The endotoxin level of our recombinant protein is assessed through the widely employed Limulus amebocyte lysate (LAL) assay. When filling out the inquiry form, you have the option to specify the desired endotoxin levels for the recombinant ACCN2 protein.
Our high-purity recombinant proteins is ideal for various biophysics-related research purposes, including structural elucidation, molecular dynamics simulations, and interaction studies.
ACCN2 is widely expressed in the central nervous system, particularly in regions associated with sensory perception and pain processing, such as the dorsal root ganglia, trigeminal ganglia, and spinal cord. It is also found in other tissues like the heart, lungs, gastrointestinal tract, and kidney.
ACCN2 has been implicated in neuronal processes, including synaptic transmission, pain perception, and modulation of neuronal excitability. It is involved in acid-induced currents in sensory neurons, contributing to the detection and transmission of acidic stimuli.
We employ rigorous quality control measures to ensure the activity and quality of recombinant protein products. These measures may include functional assays to assess the protein's ability to perform its intended biological function. Additionally, analytical techniques such as SDS-PAGE and mass spectrometry are used to verify the protein's identity and confirm its integrity.
Customer Reviews (3)
Write a reviewThe high purity of Creative BioMart's recombinant ACCN2 protein made it ideal for my downstream applications.
I am glad I chose the recombinant ACCN2 protein from Creative BioMart. It met all my research needs and was of excellent quality.
The recombinant protein product was well-packaged and delivered promptly. I had a great experience purchasing from Creative BioMart.
Ask a Question for All ACCN2 Products
Required fields are marked with *
My Review for All ACCN2 Products
Required fields are marked with *