ACSL4A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zebrafish | ACSL4A-10920Z | Recombinant Zebrafish ACSL4A | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
ACSL4A involved in several pathways and played different roles in them. We selected most pathways ACSL4A participated on our site, such as Fatty acid biosynthesis, Fatty acid degradation, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSL4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fatty acid biosynthesis | ACSL1;OXSM;MCAT;ACAA2;ACSL4;ACSL4B;ACSL4A;ACACA;ACSL3A |
| Fatty acid degradation | ADH2-1;ACSL3;ACAA1A;CYP4A12A;GCDHB;ALDH9A1A.1;ACADVL;ACAA2;CPT2 |
| Metabolic pathways | glpK;LASS1;CERS5;MVD;NME1;SPTLC3;AGK;ATP5O;ME3 |
| Fatty acid metabolism | HSD17B12A;FADS1;ACSL1A;CPT2;ELOVL2;ACADL;TECR;ACSL4;ACSL4A |
| PPAR signaling pathway | ADIPOQ;OLR1;MMP1A;ACAA1A;PDPK1;FABP3;PCK2;FABP7A;ACSBG1 |
| Peroxisome | AGPS;PIPOX;HSD17B4;ACSL3B;NOS2A;ACOX2;PHYH;MVK;ACSL1 |
| Adipocytokine signaling pathway | LEP;PTPN11;G6PC2;IRS2;RXRGB;NFKBIB;TNFRSF1B;JAK2;TNF |
ACSL4A has several biochemical functions, for example, catalytic activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACSL4A itself. We selected most functions ACSL4A had, and list some proteins which have the same functions with ACSL4A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| catalytic activity | MOXD2;ACSL4A;DPYDB;GOT2B;HSD3B6;ETNPPL;LGI1A;ODZ4;PPTC7A |
ACSL4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSL4A here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSL4A.
- Q&As
- Reviews
Q&As (10)
Ask a questionThe ACSL4A gene has been shown to be overexpressed in several types of cancer, and it has been implicated in promoting tumor growth and survival by increasing the availability of fatty acids for energy production.
Alternative splicing of the ACSL4A gene can lead to the production of different isoforms of the protein, which may have distinct functions.
ACSL4A activity can be regulated by various factors, such as protein-protein interactions, post-translational modifications, and changes in intracellular concentrations of cofactors.
ACSL4A has been shown to contribute to cellular stress responses, such as the response to oxidative stress and ER stress.
The tertiary structure of ACSL4A consists of two domains, an N-terminal ATP-grasp domain and a C-terminal acyl-CoA synthetase domain.
The ACSL4A gene has been implicated in the development of NAFLD, a condition characterized by the accumulation of fat in the liver, through its role in promoting lipid accumulation in cells.
Several genetic variants in the ACSL4A gene have been associated with altered lipid metabolism, including changes in circulating levels of triglycerides and cholesterol.
The ACSL4A gene has been implicated in the regulation of inflammation by promoting the production of pro-inflammatory lipid mediators, such as prostaglandins and leukotrienes.
The ACSL4A gene promotes cancer cell survival by increasing the uptake and utilization of fatty acids, which can serve as an alternative energy source when glucose levels are low.
The ACSL4A gene has been shown to promote lipid droplet formation in cells by increasing the availability of fatty acids for storage.
Customer Reviews (5)
Write a reviewWonderful after-sale services, friendly and kind :)
I had high expectations for this protein, and it did not disappoint. I feel like a scientist superstar now.
I'm pretty sure this protein is better than a cup of coffee for waking me up in the morning. Thanks for the boost!
I was skeptical at first, but this protein is the real deal. Definitely a repeat customer.
I think I'm in love...with this protein. Is that weird? Oh well, it's that good.
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