AGXTA
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Zebrafish | AGXTA-480Z | Recombinant Zebrafish AGXTA | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
AGXTA involved in several pathways and played different roles in them. We selected most pathways AGXTA participated on our site, such as Alanine, aspartate and glutamate metabolism, Glycine, serine and threonine metabolism, Glyoxylate and dicarboxylate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGXTA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Alanine, aspartate and glutamate metabolism | ASPA;CAD;GFPT2;GLUL;AGXT2;GPT2;GLSA;CPS1;AGXTB |
Glycine, serine and threonine metabolism | AGXT2;DAO.1;GCAT;TDH;GRHPRB;AGXT;GRHPR;DAO.2;SARDH |
Glyoxylate and dicarboxylate metabolism | ACO1;HAO1;GCSH;AGXTB;GRHPR;SHMT1;MUT;GLULB;DLDH |
Metabolic pathways | INPP1;IMPDH2;DAO.2;UROD;PON1;GCNT2;AANAT2;CD38;SGSH |
Carbon metabolism | G6PDX;PFKMA;PKM;GLUD1;PRPS2;PKMA;AGXTA;TKTB;FBP1A |
Peroxisome | DAO.1;MVK;PMVK;MPV17;PRDX1;MLYCD;IDH1;ACSL1A;PEX16 |
AGXTA has several biochemical functions, for example, alanine-glyoxylate transaminase activity, catalytic activity, serine-pyruvate transaminase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AGXTA itself. We selected most functions AGXTA had, and list some proteins which have the same functions with AGXTA. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
alanine-glyoxylate transaminase activity | AGXTB;AGXT;AGXTA;AGXT2 |
catalytic activity | Acsm2a;MOXD1L;SYN2;PPM1NB;HPGD;FH1;MED16;DIP2C;OLFM4 |
serine-pyruvate transaminase activity | AGXTB;AGXT;AGXTA |
transaminase activity | AGXTA;CCBL1;GPT2L;GOT1L1;PHYKPL;AMT;AGXT2L1;GOT2B;GOT2A |
transferase activity | ELOVL4B;GOT2B;PFKFB2A;WNK2;NTRK2B;ZDHHC15B;UGT1B2;PTAR1;ZDHHC13 |
AGXTA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGXTA here. Most of them are supplied by our site. Hope this information will be useful for your research of AGXTA.
- Q&As
- Reviews
Q&As (10)
Ask a questionAGXTA activity levels can vary depending on age, gender, and genetic background, contributing to differences in oxalate metabolism and the risk of developing kidney stones.
AGXTA is a peroxisomal enzyme that participates in the glyoxylate metabolic pathway, which is vital for peroxisomal function and the maintenance of peroxisomal homeostasis.
AGXTA mutations result in the impaired function of the enzyme, leading to the accumulation of glyoxylate, which is then converted into oxalate. High oxalate levels can cause kidney stones and kidney damage.
Structural biology techniques can provide atomic-level details of AGXTA's active site and substrate-binding interactions, elucidating the enzymatic process of glyoxylate metabolism.
Mutations in the AGXT gene can lead to the deficiency or malfunction of AGXTA, causing PH1, a rare genetic disorder characterized by excessive oxalate accumulation and kidney stone formation.
AGXTA expression is regulated by various factors, including the peroxisome proliferator-activated receptor alpha (PPARα) and hepatocyte nuclear factor 4 alpha (HNF4α). It is predominantly expressed in the liver, but also found in the kidney and other tissues.
AGXTA may have interactions with other enzymes or proteins involved in peroxisomal metabolism and could play a role in various cellular processes beyond glyoxylate metabolism.
Yes, certain dietary components, such as vitamin B6, calcium, and oxalate-rich foods, can influence AGXTA activity and oxalate production, potentially impacting the development of kidney stones.
Pharmacogenomic studies can help identify genetic factors that influence individual responses to treatments, facilitating the development of personalized therapeutic strategies for PH1 patients.
Yes, AGXTA mutations or dysregulation have been associated with other conditions, such as focal segmental glomerulosclerosis (FSGS) and idiopathic calcium oxalate urolithiasis.
Customer Reviews (5)
Write a reviewThe customer support team was extremely helpful and responsive, providing detailed information about the products.
Impeccable quality!
My lab is never running out of this recombination protein – it's become an essential part of our experiments.
They offer excellent value for the price.
What a difference this protein has made in my research – truly outstanding.
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