AKT2L
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Zebrafish | AKT2L-12081Z | Recombinant Zebrafish AKT2L | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
AKT2L involved in several pathways and played different roles in them. We selected most pathways AKT2L participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKT2L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
MAPK signaling pathway | PRKCBA;CD14;RELB;TGFB3;FGF5;PPM1AB;HSPB1;PPP3CB;RAP1B |
ErbB signaling pathway | NCK2;MAP2K2;PRKCG;GSK3AA;PIK3CG;ABL1;CAMK2G1;NRG1;BTC |
FoxO signaling pathway | IRS1;MAPK12;TGFB1A;SGK2;IL6;PRKAG2;GABARAPA;MAPK3;INSB |
mTOR signaling pathway | PIK3CB;PTENB;RPTOR;INS1;MAPK1;AKT3A;RPS6KB1;RPS6;PIK3R1 |
Apoptosis | PRKAR2AB;IL1RAP;PPP3CC;SATB1;CASP4;BCL2L11;Gzmg;CAPN2L;HDR |
Adrenergic signaling in cardiomyocytes | PIK3CA;CACNA2D1;GNA11A;CALM3A;SLC8A1;SCN1BA;TPM4;CACNA1SA;PLCB3 |
VEGF signaling pathway | MAPK13;MAPK3;AKT2;MAPK14B;MAPKAPK3;PIK3R5;SPHK2;PXNA;PRKCBB |
Focal adhesion | LAMC1;PRKCB;VEGFC;ARHGAP5;COL1A1A;TLN2A;CCND2A;RAF1A;PRKCG |
Tight junction | MYL9B;EXOC4;YES1;PRKCA;CLDNJ;ACTN2;MYH1A;PPP2CA;MYL12.2 |
Toll-like receptor signaling pathway | IFNA2;NFKB1;TICAM2;IFNA7;IFNB;TLR1;IRAK4;IFNA1;CCL4L1 |
Jak-STAT signaling pathway | AOX2P;PIK3R5;IL13;BCL2A;IL11RA2;PTPN2B;Ifna11;IFNA14;CRFB16 |
Insulin signaling pathway | FLOT2;SREBF1;PPP1CBL;PHKB;PTPN1;CALM3B;G6PC2;SH2B2;BAD |
Progesterone-mediated oocyte maturation | GNAI2;PKMYT1;RPS6KA1;ANAPC1;ADCY1A;ANAPC13;CDC25B;ANAPC7;SPDYB |
Adipocytokine signaling pathway | ACSL1;AGRP;ACSL1A;ACSL3A;PRKCQ;PPARAB;SOCS3;ACSL3;TNF |
Insulin resistance | PIK3CG;PDPK1B;TNF;PIK3R3A;AKT2;SLC27A1A;MAPK10;SREBF1;RPS6KA3A |
AKT2L has several biochemical functions, for example, ATP binding, kinase activity, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AKT2L itself. We selected most functions AKT2L had, and list some proteins which have the same functions with AKT2L. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
ATP binding | KARS;PKN1;ABCB5;STK16;ERBB3B;TNIK;DDX19;RAD51L3;IDE |
kinase activity | PDXK;PKM;ZNF143B;DYRK1AA;CDK5R1;NUCKS1A;STK24B;cka1;NEK1 |
nucleotide binding | PTK6B;DNM2B;D19ERTD386E;SEPT8B;HNRNPC;RAVER1;SNRNP200;HNRNPA3;U2AF2 |
protein kinase activity | GM4922;CSNK1G2A;MAPK12A;PLK5;BUB1B;MAP3K1;RPS6KB2;PDPK1A;PDK4 |
protein serine/threonine kinase activity | BRAF;RIOK3;BUB1B;ULK3;MAP2K5;MAP3K10;DCLK1;ADCK2;STK4 |
transferase activity | STK35L;FUT8A;NUCKS1A;HIPK2;ZNF143B;METTL8;CHST3A;GALNTL4;FKTN |
AKT2L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKT2L here. Most of them are supplied by our site. Hope this information will be useful for your research of AKT2L.
- Q&As
- Reviews
Q&As (9)
Ask a questionThe involvement of AKT2L in diseases has not been reported or studied extensively due to limited knowledge about its functions. It is possible that dysregulation of AKT2L or its interaction with other signaling pathways may contribute to diseases, but more research is required to establish any disease associations.
AKT2L is a variant or isoform of AKT2, which means they have a similar amino acid sequence but may have some functional differences. One notable difference is that AKT2L lacks the specific phosphorylation site (Serine 473) found in AKT2, which is crucial for its activation. This suggests that AKT2L may have altered or attenuated activity compared to AKT2.
Since AKT2L is not well-characterized, there are currently no known therapeutic applications or targeting strategies specific to AKT2L protein. Further studies are needed to determine its potential therapeutic relevance.
The tissue expression pattern of AKT2L protein is not well-documented. It is possible that AKT2L follows a similar expression pattern as AKT2, with higher expression in insulin-responsive tissues like skeletal muscle, adipose tissue, and the liver.
As AKT2L is not extensively studied, information about mutations or genetic alterations specific to AKT2L is scarce in the current scientific literature. Further research is needed to investigate this aspect.
At present, there are no known drug development strategies or therapeutics specifically targeting AKT2L. Since it is not well-studied, there is limited knowledge about its potential as a therapeutic target. However, with further investigation and understanding of its functions and involvement in diseases, AKT2L may become a target of interest for drug development in the future.
The regulatory mechanisms governing AKT2L activity are not well-known. However, it is plausible that AKT2L may be regulated by similar mechanisms as AKT2, including phosphorylation, dephosphorylation, and protein-protein interactions. Further research is required to uncover the specific regulatory processes for AKT2L.
The functions of AKT2L protein are not well-characterized and remain largely unknown. Due to its similarity to AKT2, it is possible that AKT2L may also be involved in cell survival, growth, metabolism, and glucose homeostasis.
The specific binding partners or interacting proteins of AKT2L have not been extensively identified or studied. It is possible that AKT2L may interact with similar partners as AKT2, including proteins involved in insulin signaling and other cellular processes. Further research is needed to elucidate the precise interactome of AKT2L.
Customer Reviews (4)
Write a reviewBy selecting the AKT2L protein, I am confident that I am equipping myself with a superior tool that will not only meet but exceed my experimental needs.
I am confident that incorporating the AKT2L protein into my research will yield accurate and reliable results, enabling deeper insights into cellular processes
The AKT2L protein stands out as a high-quality protein that perfectly caters to my experimental requirements.
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