aldh2
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  • Official Full Name
  • aldehyde dehydrogenase 2 family (mitochondrial)
  • Background
  • This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while ~50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.
  • Synonyms
  • ALDH2; aldehyde dehydrogenase 2 family (mitochondrial); aldehyde dehydrogenase, mitochondrial; ALDH class 2; liver mitochondrial ALDH; acetaldehyde dehydrogenase 2; nucleus-encoded mitochondrial aldehyde dehydrogenase 2; ALDM; ALDHI; ALDH-E2; MGC1806
Cat.#:ALDH2-27037THTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALDH2
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Cat.#:ALDH2-27039THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALDH2, His-tagged
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Cat.#:ALDH2-130HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ALDH2 protein, MYC/DDK-tagged
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Cat.#:ALDH2-131HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ALDH2 protein, GST-tagged
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Cat.#:ALDH2-139HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALDH2 protein
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Cat.#:ALDH2-2122HTag:His/S
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALDH2 protein, His & S-tagged
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Cat.#:ALDH2-444HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ALDH2 Protein, GST-tagged
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Cat.#:ALDH2-1525MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ALDH2 Protein
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Cat.#:Aldh2-83MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Aldh2, His-tagged
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Cat.#:Aldh2-3264RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Aldh2, His-tagged
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Cat.#:ALDH2-620RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ALDH2 Protein
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Cat.#:ALDH2-8918HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ALDH2 293 Cell Lysate
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Cat.#:Kit-0076Tag:
Source (Host):Species:
Product nameMitochondrial Aldehyde Dehydrogenase (ALDH2) Activity Assay Kit
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ALDH2 Related Articles

Lai, CL; Yao, CT; et al. Dominance of the Inactive Asian Variant Over Activity and Protein Contents of Mitochondrial Aldehyde Dehydrogenase 2 in Human Liver. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 38:44-50(2014).
Yokoyama, A; Mizukami, T; et al. Genetic Polymorphisms of Alcohol Dehydrogenase-1B and Aldehyde Dehydrogenase-2 and Liver Cirrhosis, Chronic Calcific Pancreatitis, Diabetes Mellitus, and Hypertension Among Japanese Alcoholic Men. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 37:1391-1401(2013).