ALDOAA
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zebrafish | ALDOAA-9727Z | Recombinant Zebrafish ALDOAA | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
ALDOAA involved in several pathways and played different roles in them. We selected most pathways ALDOAA participated on our site, such as Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Fructose and mannose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALDOAA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycolysis / Gluconeogenesis | ALDOCA;G6PCA.1;ADH1C;ENO1;ALDH1A3;ALDH2.1;HK1;PDHB;ENO2 |
| Pentose phosphate pathway | deoC;ALDOCB;PFKMB;RBKS;G6PD;H6PD;RPE;ALDOA;PGD |
| Fructose and mannose metabolism | AKR1B7;KHK;ALDOB;FBP1B;PFKMA;AKR1B1L;TPI1A;TIGARA;PFKFB1 |
| Metabolic pathways | NDUFB5;COX6A1;SARDH;POLG2;PPAP2CB;CKMT1;GK2;UGT1A1;ACAT2 |
| Carbon metabolism | ALDH6A1;ACADS;ALDOB;SDHB;ALDOAA;HAO2;OGDH;IDH3A;CPS1 |
| Biosynthesis of amino acids | PFKMA;ACO2;ACY1;PRPS1B;TKT;IDH2;GPT2L;GLULC;PRPS1L1 |
ALDOAA has several biochemical functions, for example, catalytic activity, fructose-bisphosphate aldolase activity, lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALDOAA itself. We selected most functions ALDOAA had, and list some proteins which have the same functions with ALDOAA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| catalytic activity | RSAD1;ACSL1A;LGI1A;LANCL3;ITPK1;PCXB;NDUFA9A;MOXD2;ACSL1 |
| fructose-bisphosphate aldolase activity | ALDOCA;ALDOB;ALDOAB;ALDOA;ALDOAA;ALDOC;ALDOCB |
| lyase activity | MVDA;GC2;IRG1L;ENO1A;AGXT2L2;ADCY1A;POLL;PTPLA;CAR3 |
ALDOAA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALDOAA here. Most of them are supplied by our site. Hope this information will be useful for your research of ALDOAA.
- Q&As
- Reviews
Q&As (6)
Ask a questionResearch on ALDOAA protein is still actively conducted, mainly focusing on its role in glycolysis and metabolism. Studies aim to better understand its structure, regulation, and potential implications in various diseases and conditions. Additionally, research is exploring the potential use of ALDOAA as a therapeutic target for metabolic disorders.
Yes, there are known mutations and genetic variations in the ALDOAA gene. Some of these variations have been associated with certain metabolic disorders, such as nonspherocytic hemolytic anemia and hereditary fructose intolerance. These variations can lead to reduced or altered activity of ALDOAA protein, affecting its function in the glycolysis pathway.
ALDOAA protein has been found to have altered expression levels in various types of cancer. It is suggested that upregulation of ALDOAA in cancer cells enhances the glycolysis pathway, allowing cancer cells to produce energy even under conditions of low oxygen (known as the Warburg effect). This increased glycolytic activity supports the rapid proliferation and growth of cancer cells.
Currently, there are no specific drugs directly targeting ALDOAA protein. However, as it plays a central role in glycolysis, targeting other enzymes and regulators in the glycolytic pathway can indirectly affect the activity of ALDOAA. For instance, several anticancer drugs have been developed to inhibit enzymes involved in glycolysis, which indirectly affects ALDOAA function.
ALDOAA protein is regulated by various factors, including cellular energy levels and signaling pathways. Its activity can be regulated via post-translational modifications, such as phosphorylation, and by the availability of its substrates and cofactors. Additionally, ALDOAA protein is part of a multi-enzyme complex called the glycolytic metabolon, which enhances its efficiency in the glycolysis pathway.
ALDOAA protein belongs to the class I aldolase family and consists of four identical subunits. Each subunit has an active site where the catalytic reaction takes place. The protein has a barrel-shaped structure formed by a beta-sheet core, with alpha-helices positioned on the outer surface. The active site contains specific amino acid residues that play a crucial role in the catalytic function.
Customer Reviews (4)
Write a reviewThe manufacturer's commitment to excellence is truly commendable, especially when it comes to their outstanding technical support.
With their extensive knowledge and expertise, I am assured that any challenges or issues I may encounter during my research will be efficiently resolved.
I am highly impressed with the ALDOAA protein as it is of exceptionally high quality, and I am confident that it will perfectly meet the specific requirements of my experiments.
Such dedicated support makes me feel confident in my choice of using the ALDOAA protein for my experiments.
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