ANKZF1
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Official Full Name
ankyrin repeat and zinc finger domain containing 1
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Overview
Ankyrin repeat and zinc finger domain-containing protein 1 is a protein that in humans is encoded by the ANKZF1 gene. -
Synonyms
ANKZF1; ankyrin repeat and zinc finger domain containing 1; ankyrin repeat and zinc finger domain-containing protein 1; FLJ10415; ZNF744; Ankyrin repeat and zinc finger domain containing protein 1; ANKZF 1; ANKZF1 protein; FLJ13144; Zinc finger protein 744;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
ANKZF1 involved in several pathways and played different roles in them. We selected most pathways ANKZF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANKZF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ANKZF1 has several biochemical functions, for example, metal ion binding, protein binding, contributes_to ubiquitin-specific protease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANKZF1 itself. We selected most functions ANKZF1 had, and list some proteins which have the same functions with ANKZF1. You can find most of the proteins on our site.
Function | Related Protein |
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metal ion binding | ZC3H12A;ANKMY1;STAMBPA;GGTA1;ZHX3;SUZ12A;ZDHHC24;PRDM12;CSRP1A |
protein binding | EGLN3;FAM189B;IFT172;CLIC1;RMI1;GALNT2;TWIST1;TNIP1;CNOT3 |
contributes_to ubiquitin-specific protease activity | USP22;TNIP1;ANKZF1 |
ANKZF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANKZF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANKZF1.
ORF; CA2; CRK; EMS1; ypeB; AURKB; NRSN2; DNAJB11
- Q&As
- Reviews
Q&As (7)
Ask a questionSome studies have reported genetic variations and mutations in the ANKZF1 gene. These variations may include single nucleotide polymorphisms (SNPs) or more significant genetic alterations. However, the functional consequences and clinical significance of these genetic variants are not yet fully understood and require further investigation.
ANKZF1 is a nuclear protein that primarily functions as a transcriptional regulator. It can bind to specific DNA sequences and modulate the expression of target genes. ANKZF1 has also been implicated in DNA repair processes, suggesting a role in maintaining genome stability. It may interact with other proteins involved in chromatin remodeling or transcriptional regulation to exert its biological effects.
Currently, no specific diseases or disorders have been directly linked to ANKZF1 abnormalities. However, altered expression or mutations in the ANKZF1 gene have been reported in certain cancers, including breast cancer and hepatocellular carcinoma. Further research is needed to fully understand the clinical significance of ANKZF1 in disease pathology.
The clinical relevance and therapeutic potential of ANKZF1 are still being investigated. As mentioned earlier, ANKZF1 has been implicated in certain cancer types; therefore, it holds promise as a potential therapeutic target or diagnostic/prognostic marker. However, more research is needed to fully understand the role of ANKZF1 in disease processes and develop targeted therapies.
ANKZF1 shows a relatively widespread expression pattern. It is expressed in various tissues and organs throughout the body, including the brain, heart, liver, kidney, lung, and skeletal muscle. The level of ANKZF1 expression may vary between different tissues and cell types.
Current research on ANKZF1 aims to understand its role in various biological processes and its potential implications in disease pathology. Scientists are investigating ANKZF1's involvement in cancer development and progression, as well as its interactions with other proteins and regulatory pathways. Additionally, efforts are being made to determine the therapeutic potential of targeting ANKZF1 in specific diseases.
The specific protein interactors of ANKZF1 are not extensively characterized. However, some studies suggest that ANKZF1 interacts with other transcriptional regulators, chromatin remodelers, and DNA repair proteins. Further research is necessary to identify and validate these interaction partners, as well as determine their functional significance.
Customer Reviews (3)
Write a reviewthe ANKZF1 protein comes highly recommended for its exceptional performance in Western blot analysis and its utility in protein electron microscopy structure analysis.
Its compatibility with various methodologies further enhances its value as a research tool, making it a go-to choice for investigating ANKZF1 protein function and molecular interactions.
Its versatility and reliability make it an excellent choice for researchers seeking to delve deeper into the mechanisms and functions of the ANKZF1 protein.
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